Product Introduction:
Annifer 1 mg is a prescription anti-cancer medication mainly used for postmenopausal women with hormone receptor-positive (HR+) breast cancer. It belongs to the aromatase inhibitor class, reducing estrogen levels to prevent tumor growth and recurrence.
Uses of Annifer 1 mg
Annifer 1 mg is prescribed for:
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Hormone Receptor-Positive (HR+) Breast Cancer – Used in postmenopausal women to slow cancer growth.
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Adjuvant Therapy for Early Breast Cancer – Given after surgery to prevent cancer recurrence.
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Metastatic Breast Cancer – Helps manage advanced-stage breast cancer.
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Neoadjuvant Therapy – Used before surgery to shrink tumors.
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Breast Cancer Prevention – In some cases, it helps reduce the risk of breast cancer in high-risk women.
How Annifer 1 mg Works (Mechanism of Action):
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Anastrozole blocks the aromatase enzyme, which converts androgens into estrogen.
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Lowering estrogen levels helps slow or stop the growth of hormone-sensitive breast cancer.
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It is only effective in postmenopausal women, as estrogen is primarily produced in peripheral tissues after menopause.
Dosage of Annifer 1 mg
Recommended Dosage:
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Standard dose: 1 mg once daily.
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Treatment duration: Typically 5 years, but may vary based on medical advice.
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Dosage adjustments: Rarely needed unless severe side effects occur.
📌 Always follow your oncologist’s instructions for best results.
Method of Administration (How to Take It)
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Can be taken with or without food.
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Swallow the tablet whole with water—do not crush, chew, or break it.
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Take at the same time every day for maximum effectiveness.
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If vomiting occurs after taking the dose, do not retake it—wait for the next scheduled dose.
Side Effects of Annifer 1 mg
Common Side Effects:
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Hot flashes
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Joint pain and stiffness
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Fatigue and weakness
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Osteoporosis (bone thinning, increased fracture risk)
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Headache and dizziness
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Nausea and vomiting
Severe Side Effects (Seek Medical Help Immediately):
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Severe osteoporosis, leading to fractures
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Heart problems (chest pain, shortness of breath, irregular heartbeat)
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Liver damage (jaundice, dark urine, stomach pain)
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Blood clots (sudden numbness, vision changes, difficulty speaking)
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Severe allergic reactions (rash, swelling, breathing problems)
⚠️ Regular bone density and heart function tests are recommended.
Precautions Before Taking Annifer 1 mg
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Pregnancy & Breastfeeding: Not safe—can cause harm to the baby.
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Bone Health: May increase the risk of osteoporosis—calcium and vitamin D supplements may be needed.
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Heart Conditions: May raise the risk of heart disease or high cholesterol.
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Liver or Kidney Disease: Requires dose adjustment or close monitoring.
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Drowsiness or Dizziness: Avoid activities like driving if affected.
Drug Interactions (Medications That May Interact)
Annifer 1 mg can interact with:
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Tamoxifen – Reduces the effectiveness of Anastrozole.
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Estrogen Therapies (HRT, birth control pills) – Counteracts the drug’s effect.
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Blood Thinners (Warfarin, Aspirin, Heparin) – Increases bleeding risk.
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Rifampin & Carbamazepine – May lower Anastrozole levels, reducing effectiveness.
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Corticosteroids – Can increase the risk of osteoporosis.
⚠️ Always inform your doctor about any medications you are taking.
Allergy Warnings
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Do not take Annifer if allergic to Anastrozole or its ingredients.
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Signs of an allergic reaction:
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Swelling of face, lips, or throat
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Difficulty breathing
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Severe rash or itching
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Dizziness or fainting
🚨 Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
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Store at room temperature (15°C - 30°C / 59°F - 86°F).
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Keep in original packaging to protect from moisture and light.
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Keep away from children and pets.
Overdose Information
Symptoms of overdose:
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Severe nausea and vomiting
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Dizziness or fainting
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Liver or kidney damage symptoms (yellow skin, confusion)
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Severe weakness or drowsiness
What to do in case of overdose?
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Seek immediate medical attention.
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Hospitalization may be required for supportive care.
Missed Dose Instructions
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If missed by less than 12 hours: Take the dose as soon as possible.
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If missed by more than 12 hours: Skip the missed dose and take the next scheduled dose.
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Do not take a double dose to make up for a missed one.
