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Arimidex 1mg - Anastrozole Tablets

Arimidex 1 mg is a prescription medication containing Anastrozole, an aromatase inhibitor used for the treatment of hormone receptor-positive (HR+) breast cancer in postmenopausal women. It works by reducing estrogen production, which helps slow or stop the growth of hormone-sensitive tumors.

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General Information:
Generic Name: Anastrozole
Brand Name: Arimidex
Packing: Blister pack
Strength: 1 mg
Company: Astrazeneca Pharma India Ltd
Form: Oral tablet
Category: Aromatase Inhibitor, Anti-Cancer Drug
Product Introduction:
Arimidex 1 mg is a well-known aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women. It is often prescribed for early-stage and metastatic breast cancer and is considered a first-line treatment in many cases.

Uses of Arimidex 1 mg
Arimidex 1 mg is prescribed for the following conditions:
  1. Hormone Receptor-Positive Breast Cancer – Helps slow tumor growth in postmenopausal women.
  2. Adjuvant Therapy for Early Breast Cancer – Used after surgery to prevent cancer recurrence.
  3. Metastatic Breast Cancer – Helps manage advanced-stage breast cancer.
  4. Neoadjuvant Therapy – Used before surgery to shrink tumors.
  5. Breast Cancer Prevention – May be prescribed to reduce the risk of breast cancer in high-risk women.

How Arimidex 1 mg Works (Mechanism of Action):
  1. Anastrozole blocks the aromatase enzyme, preventing the conversion of androgens into estrogen.
  2. Since estrogen fuels hormone-sensitive breast tumors, reducing its levels slows or stops tumor growth.
  3. It is only effective in postmenopausal women, as their primary source of estrogen is peripheral tissues rather than the ovaries.

Dosage of Arimidex 1 mg
Recommended Dosage:
  1. Standard dose: 1 mg once daily.
  2. Duration of treatment: Typically 5 years, but may vary based on medical evaluation.
  3. Dosage adjustments: Generally not needed unless severe side effects occur.
📌 Follow your doctor’s instructions for best results.

Method of Administration (How to Take It)
  1. Can be taken with or without food.
  2. Swallow the tablet whole with water—do not crush, chew, or break it.
  3. Take at the same time every day for better effectiveness.
  4. If vomiting occurs after taking the dose, do not retake it—wait for the next scheduled dose.

Side Effects of Arimidex 1 mg
Common Side Effects:
  1. Hot flashes
  2. Joint pain and stiffness
  3. Fatigue and weakness
  4. Osteoporosis (bone thinning, increased fracture risk)
  5. Headache and dizziness
  6. Nausea and vomiting
Severe Side Effects (Seek Medical Help Immediately):
  1. Severe osteoporosis leading to fractures
  2. Heart problems (chest pain, shortness of breath, irregular heartbeat)
  3. Liver damage (jaundice, dark urine, stomach pain)
  4. Blood clots (sudden numbness, vision changes, difficulty speaking)
  5. Severe allergic reactions (rash, swelling, breathing problems)
⚠️ Regular bone density and heart function tests are recommended.

Precautions Before Taking Arimidex 1 mg
  1. Pregnancy & Breastfeeding: Not safe—can cause harm to the baby.
  2. Bone Health: Increases the risk of osteoporosis—calcium and vitamin D supplements may be needed.
  3. Heart Conditions: May raise the risk of heart disease or high cholesterol.
  4. Liver or Kidney Disease: Requires dose adjustment or close monitoring.
  5. Drowsiness or Dizziness: Avoid activities like driving if affected.

Drug Interactions (Medications That May Interact)
Arimidex 1 mg can interact with:
  1. Tamoxifen – Reduces the effectiveness of Anastrozole.
  2. Estrogen Therapies (HRT, birth control pills) – Counteracts the drug’s effect.
  3. Blood Thinners (Warfarin, Aspirin, Heparin) – Increases bleeding risk.
  4. Rifampin & Carbamazepine – May lower Anastrozole levels, reducing effectiveness.
  5. Corticosteroids – Can increase the risk of osteoporosis.
⚠️ Always inform your doctor about any medications you are taking.

Allergy Warnings
  1. Do not take Arimidex if allergic to Anastrozole or its ingredients.
  2. Signs of an allergic reaction:
    1. Swelling of face, lips, or throat
    2. Difficulty breathing
    3. Severe rash or itching
    4. Dizziness or fainting
🚨 Seek emergency medical help if an allergic reaction occurs.

Storage Instructions
  1. Store at room temperature (15°C - 30°C / 59°F - 86°F).
  2. Keep in original packaging to protect from moisture and light.
  3. Keep away from children and pets.

Overdose Information
Symptoms of overdose:
  1. Severe nausea and vomiting
  2. Dizziness or fainting
  3. Liver or kidney damage symptoms (yellow skin, confusion)
  4. Severe weakness or drowsiness
What to do in case of overdose?
  1. Seek immediate medical attention.
  2. Hospitalization may be required for supportive care.

Missed Dose Instructions
  1. If missed by less than 12 hours: Take the dose as soon as possible.
  2. If missed by more than 12 hours: Skip the missed dose and take the next scheduled dose.
  3. Do not take a double dose to make up for a missed one.

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