Product Introduction:
Caboplat 150mg is a widely used chemotherapy injection for treating various solid tumors. It is known for its effectiveness in ovarian cancer, lung cancer, and other malignancies, often used alone or in combination with other chemotherapy drugs.
Uses of Caboplat 150mg
Caboplat 150mg is primarily used for treating:
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Ovarian Cancer – First-line or recurrent ovarian cancer treatment.
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Lung Cancer (Non-Small Cell & Small Cell Lung Cancer - NSCLC, SCLC) – Used in combination with other drugs.
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Breast Cancer – Used in triple-negative breast cancer cases.
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Bladder Cancer – Helps shrink tumors before surgery.
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Head and Neck Cancers – Often used as part of combination therapy.
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Testicular Cancer & Other Solid Tumors – Sometimes used when cisplatin is not an option.
How Caboplat 150mg Works (Mechanism of Action):
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Carboplatin is a platinum-based drug that forms strong bonds with cancer cell DNA.
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This prevents DNA replication, stopping cancer cell growth.
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The damaged cells eventually die, leading to tumor shrinkage.
✅ It is less toxic to the kidneys than cisplatin, making it a preferred choice for certain patients.
Dosage of Caboplat 150mg
Typical Recommended Dose:
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Ovarian Cancer: 300–400 mg/m² IV every 3-4 weeks.
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Lung Cancer: AUC 5-6 mg/mL/min IV every 3 weeks (in combination with Paclitaxel).
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Breast Cancer: Similar dosing as lung cancer (varies by patient).
⚠️ Dosage is adjusted based on kidney function, body surface area, and blood counts.
Method of Administration (How to Take It)
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Administered as an intravenous (IV) infusion over 15–60 minutes.
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Given in a hospital or clinic setting under medical supervision.
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Pre-medications may be given to reduce nausea and allergic reactions.
Side Effects of Caboplat 150mg
Common Side Effects:
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Nausea & Vomiting
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Fatigue & Weakness
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Low Blood Cell Counts (Anemia, Neutropenia, Thrombocytopenia)
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Hair Loss
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Loss of Appetite
Severe Side Effects (Seek Immediate Medical Help):
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Severe allergic reactions (rash, difficulty breathing, swelling)
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Kidney or Liver Damage (Yellowing of skin, dark urine)
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Hearing Loss (Ototoxicity)
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Severe infections due to low white blood cells
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Uncontrolled bleeding or bruising
🚨 Contact a doctor immediately if severe symptoms occur.
Precautions Before Taking Caboplat 150mg
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Kidney Disease: Requires dose adjustment.
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Blood Disorders (Low Platelets, Anemia): Increased risk of bleeding/infections.
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Pregnancy & Breastfeeding: Not safe – Can harm the fetus.
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Hearing Problems: Monitor for hearing loss.
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Dehydration Risk: Stay hydrated to protect kidney function.
Drug Interactions (Medications That May Interact)
Caboplat 150mg may interact with:
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Aminoglycoside Antibiotics (Gentamicin, Amikacin): Increases kidney toxicity.
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Diuretics (Furosemide): Can worsen hearing loss and kidney damage.
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Other Chemotherapy Drugs (Paclitaxel, Cisplatin): Requires close monitoring.
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Blood Thinners (Warfarin, Heparin): Increases bleeding risk.
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NSAIDs (Ibuprofen, Naproxen): Can increase kidney damage risk.
⚠️ Inform your doctor about all medications you are taking.
Allergy Warnings
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Do not take if allergic to Carboplatin, Cisplatin, or other platinum-based drugs.
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Symptoms of an allergic reaction:
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Rash, Itching
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Swelling of face or throat
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Difficulty breathing
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Dizziness
🚨 Seek emergency medical help if allergic symptoms occur.
Storage Instructions
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Store at 2°C - 8°C (Refrigerated).
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Keep in the original packaging, protected from light.
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Do not freeze.
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Keep out of reach of children.
Overdose Information
Symptoms of Overdose:
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Severe nausea & vomiting
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Extreme fatigue & dizziness
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Uncontrolled bleeding or bruising
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Severe kidney damage
What to Do in Case of Overdose?
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Seek emergency medical help immediately.
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Hospitalization may be required for supportive treatment.
Missed Dose Instructions
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If a dose is missed, consult the doctor immediately.
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Do not double the dose to make up for a missed one.
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Rescheduling may be required.
