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Capsy 500mg - Capecitabine Tablets

Capsy 500mg contains Capecitabine, an oral chemotherapy drug used to treat breast, colon, and gastric cancers. It is a prodrug of 5-fluorouracil (5-FU), meaning it converts into its active form inside the body, selectively targeting cancer cells while minimizing damage to normal cells.

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General Information:
Generic Name: Capecitabine
Brand Name: Capsy
Packing: 10 Tabs in Strip
Strength: 500mg
Manufacturer: Intas Pharmaceuticals Pvt.
Form: Tablet (Oral Use)
Category: Antimetabolite, Chemotherapy Drug
Product Introduction:
Capsy 500mg is an oral chemotherapy medication used to treat various cancers, either alone or in combination with other chemotherapy agents. It is commonly prescribed for breast, colorectal, and stomach cancer.

Uses of Capsy 500mg
Capsy 500mg is primarily used for the treatment of:
  1. Metastatic Colorectal Cancer – Used alone or with other drugs.
  2. Metastatic Breast Cancer – Often combined with Docetaxel when other treatments fail.
  3. Gastric (Stomach) Cancer – Used as a first-line treatment.
  4. Esophageal Cancer – Helps in reducing tumor size.
  5. Pancreatic Cancer – Sometimes used in off-label treatments.
  6. Adjuvant Therapy (Post-Surgery Cancer Treatment) – To prevent cancer recurrence.

How Capsy 500mg Works (Mechanism of Action):
  1. Capecitabine is a prodrug – It gets converted into 5-Fluorouracil (5-FU) inside the body.
  2. 5-FU interferes with DNA & RNA synthesis in cancer cells.
  3. This disrupts cancer cell division, leading to tumor shrinkage and cell death.
It selectively targets cancer cells while sparing normal cells, reducing toxicity.

Dosage of Capsy 500mg
Typical Recommended Dose:
  1. Colorectal Cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day break.
  2. Breast Cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day break (often combined with Docetaxel).
  3. Stomach Cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day break.
⚠️ Dosage depends on body weight, kidney function, and doctor’s prescription.

Method of Administration (How to Take It)
  1. Take Capsy 500mg within 30 minutes after a meal with water.
  2. Swallow the tablet whole (Do not crush or chew).
  3. Follow the prescribed schedule (14-day treatment + 7-day break cycle).

Side Effects of Capsy 500mg
Common Side Effects:
  1. Hand-Foot Syndrome (Redness, peeling, and pain in hands & feet)
  2. Nausea, Vomiting, and Diarrhea
  3. Fatigue & Weakness
  4. Loss of Appetite & Weight Loss
  5. Mouth Sores & Dry Mouth
Severe Side Effects (Seek Immediate Medical Help):
  1. Severe diarrhea & dehydration
  2. Irregular heartbeat or chest pain
  3. Liver toxicity (Yellowing of skin, dark urine)
  4. Severe hand-foot syndrome (blisters, ulcers, swelling)
  5. Low white blood cell count (Risk of infections)
🚨 If severe symptoms occur, contact a doctor immediately.

Precautions Before Taking Capsy 500mg
  1. Kidney or Liver Disease: Dose adjustments may be required.
  2. Heart Problems: Can cause irregular heartbeat.
  3. Pregnancy & Breastfeeding: Not safe – Can cause fetal harm.
  4. Diabetes: Monitor blood sugar levels carefully.
  5. Dehydration Risk: Stay hydrated to prevent severe diarrhea.

Drug Interactions (Medications That May Interact)
Capsy 500mg may interact with:
  1. Warfarin & Blood Thinners: Increases bleeding risk.
  2. Phenytoin (Seizure Medication): Increases phenytoin toxicity.
  3. Leucovorin (Folic Acid): Increases Capecitabine toxicity.
  4. Antacids (Magnesium, Aluminum Hydroxide): May affect drug absorption.
  5. Live Vaccines: Avoid while on chemotherapy.
⚠️ Always inform your doctor about all medications you are taking.

Allergy Warnings
  1. Do not take if allergic to Capecitabine or Fluorouracil (5-FU).
  2. Symptoms of an allergic reaction:
    1. Swelling, Rash, Itching
    2. Shortness of breath, Chest tightness
    3. Severe dizziness
🚨 Seek emergency medical help if allergic symptoms occur.

Storage Instructions
  1. Store at room temperature (20°C - 25°C).
  2. Keep away from moisture and direct sunlight.
  3. Store in the original packaging.
  4. Keep out of reach of children.

Overdose Information
Symptoms of Overdose:
  1. Severe diarrhea & vomiting
  2. Severe hand-foot syndrome
  3. Extreme fatigue & confusion
  4. Irregular heartbeat
What to Do in Case of Overdose?
  1. Seek emergency medical help immediately.
  2. Hospitalization may be required for supportive treatment.

Missed Dose Instructions
  1. If a dose is missed, take it as soon as possible.
  2. If it’s close to the next dose, skip the missed dose.
  3. Do not double the dose to make up for a missed one.

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