Product Introduction:
Mediocarb 150mg is a chemotherapy medication from the platinum-based drug class, primarily used in treating ovarian, lung, and other solid tumors. It is a less toxic alternative to cisplatin, reducing kidney and nerve toxicity risks.
Uses of Mediocarb 150mg
Mediocarb 150mg is used for treating:
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Ovarian Cancer – First-line and recurrent ovarian cancer treatment.
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Lung Cancer (NSCLC, SCLC) – Used alone or with Paclitaxel.
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Breast Cancer – Effective in treating triple-negative breast cancer.
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Bladder Cancer – Helps shrink tumors before surgery.
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Head and Neck Cancers – Often used with radiation therapy.
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Testicular & Other Solid Tumors – Alternative to cisplatin in certain cases.
How Mediocarb 150mg Works (Mechanism of Action):
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Carboplatin binds to DNA in cancer cells, forming cross-links that prevent DNA replication.
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This leads to cell cycle arrest and apoptosis (cancer cell death).
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It is less nephrotoxic (kidney-damaging) than cisplatin, but careful monitoring is still required.
✅ Works best when used in combination with other chemotherapy drugs like Paclitaxel.
Dosage of Mediocarb 150mg
Typical Recommended Dose:
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Ovarian Cancer: 300–400 mg/m² IV every 3-4 weeks.
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Lung Cancer: AUC 5-6 mg/mL/min IV every 3 weeks.
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Breast Cancer: AUC 5-6 mg/mL/min IV every 3 weeks.
⚠️ Dosage is based on kidney function, body surface area, and blood count levels.
Method of Administration (How to Take It)
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Administered via IV infusion over 15–60 minutes.
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Given in a hospital or clinic setting under medical supervision.
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Pre-medications may be required to reduce nausea and allergic reactions.
Side Effects of Mediocarb 150mg
Common Side Effects:
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Nausea & Vomiting
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Fatigue & Weakness
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Low Blood Cell Counts (Anemia, Neutropenia, Thrombocytopenia)
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Hair Loss
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Loss of Appetite
Severe Side Effects (Seek Immediate Medical Help):
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Severe allergic reactions (rash, breathing difficulty, swelling)
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Kidney or Liver Damage (Yellowing of skin, dark urine)
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Hearing Loss (Ototoxicity)
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Severe infections due to low white blood cells
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Uncontrolled bleeding or bruising
🚨 Seek immediate medical attention if severe symptoms occur.
Precautions Before Taking Mediocarb 150mg
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Kidney Disease: Requires dose adjustment.
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Blood Disorders (Low Platelets, Anemia): Increases risk of bleeding/infections.
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Pregnancy & Breastfeeding: Not safe – Can harm the fetus.
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Hearing Problems: Monitor for hearing loss.
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Dehydration Risk: Stay hydrated to protect kidney function.
Drug Interactions (Medications That May Interact)
Mediocarb 150mg may interact with:
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Aminoglycoside Antibiotics (Gentamicin, Amikacin): Increases kidney toxicity.
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Diuretics (Furosemide): Can worsen hearing loss and kidney damage.
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Other Chemotherapy Drugs (Paclitaxel, Cisplatin): Requires careful monitoring.
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Blood Thinners (Warfarin, Heparin): Increases bleeding risk.
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NSAIDs (Ibuprofen, Naproxen): Can increase kidney damage risk.
⚠️ Inform your doctor about all medications you are taking.
Allergy Warnings
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Do not take if allergic to Carboplatin, Cisplatin, or other platinum-based drugs.
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Symptoms of an allergic reaction:
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Rash, Itching
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Swelling of face or throat
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Difficulty breathing
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Dizziness
🚨 Seek emergency medical help if allergic symptoms occur.
Storage Instructions
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Store at 2°C - 8°C (Refrigerated).
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Keep in the original packaging, protected from light.
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Do not freeze.
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Keep out of reach of children.
Overdose Information
Symptoms of Overdose:
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Severe nausea & vomiting
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Extreme fatigue & dizziness
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Uncontrolled bleeding or bruising
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Severe kidney damage
What to Do in Case of Overdose?
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Seek emergency medical help immediately.
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Hospitalization may be required for supportive treatment.
Missed Dose Instructions
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If a dose is missed, consult the doctor immediately.
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Do not double the dose to make up for a missed one.
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Rescheduling may be required.
