Product Introduction:
Flexbumin 20% is a sterile, purified human albumin solution used for treating conditions that require plasma volume expansion or protein replacement. It is often used in critical care settings such as ICUs, surgery, and emergency medicine.
Uses of Flexbumin 20%
Flexbumin 20% is used for:
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Hypovolemia (Low Blood Volume): Helps restore blood circulation in severe blood loss.
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Burns & Shock: Prevents fluid loss and maintains blood pressure.
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Liver Disease & Cirrhosis: Treats ascites and low protein levels.
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Nephrotic Syndrome: Helps in kidney disease-related protein loss.
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Cardiac Surgery & Dialysis: Supports fluid balance during medical procedures.
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Acute Respiratory Distress Syndrome (ARDS): Helps maintain proper lung function.
How Flexbumin 20% Works (Mechanism of Action):
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Human Albumin is a major protein in blood plasma.
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It maintains oncotic pressure, preventing fluid leakage from blood vessels into tissues.
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It transports hormones, enzymes, and drugs in the bloodstream.
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Increases blood volume and stabilizes circulation in patients with low plasma levels.
✅ Acts as a plasma expander and helps treat low protein levels.
Dosage of Flexbumin 20%
Typical Recommended Dose:
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For Hypovolemia: 250-500 mL IV infusion, based on patient condition.
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For Burns & Shock: 100-200 mL IV, adjusted according to fluid loss.
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For Liver Disease: 50-100 mL/day to maintain albumin levels.
⚠️ Dosage varies based on patient weight, condition, and doctor’s instructions.
Method of Administration (How to Take It)
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Administered by IV infusion (intravenous drip).
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Infuse slowly to prevent volume overload.
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Dilution may be required in some conditions.
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Monitor blood pressure and kidney function during administration.
💡 Tip: Should only be given under medical supervision in hospitals or clinics.
Side Effects of Flexbumin 20%
Common Side Effects:
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Nausea & Vomiting
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Mild Fever
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Flushing (Warm Feeling)
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Headache
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Skin Rash
Serious Side Effects (Seek Medical Help):
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Allergic Reactions: Swelling, breathing difficulty, severe rash.
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Fluid Overload: Shortness of breath, swelling in legs, high blood pressure.
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Kidney Problems: Reduced urine output, swelling, severe fatigue.
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Severe Hypotension: Sudden drop in blood pressure.
🚨 Contact a doctor if serious side effects occur.
Precautions Before Taking Flexbumin 20%
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Heart or Kidney Disease: Use with caution, as it may cause fluid overload.
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Dehydration: Should be corrected before albumin infusion.
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Severe Anemia: Not recommended, as it does not provide red blood cells.
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Pregnancy & Breastfeeding: Use only if clearly needed.
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Blood Pressure Issues: Monitor for sudden increases or drops.
⚠️ Requires careful monitoring in critically ill patients.
Drug Interactions (Medications That May Interact)
Flexbumin 20% may interact with:
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Diuretics (Furosemide, Spironolactone): May alter fluid balance.
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Blood Thinners (Warfarin, Heparin): May affect clotting properties.
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ACE Inhibitors (Lisinopril, Enalapril): Can lower blood pressure excessively.
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Steroids (Prednisolone, Dexamethasone): Can increase fluid retention.
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Other IV Fluids: Should be balanced to prevent fluid overload.
⚠️ Tell your doctor about all medications you are taking.
Allergy Warnings
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Do not take if allergic to human albumin or any plasma-derived proteins.
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Symptoms of an allergic reaction:
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Difficulty breathing
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Swelling of the face, lips, or throat
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Severe itching or rash
🚨 Seek emergency medical help if allergic symptoms occur.
Storage Instructions
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Store at 2-25°C (refrigerated or room temperature).
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Do not freeze or shake the vial.
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Keep in the original container, away from direct sunlight.
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Use within 4 hours once opened.
Overdose Information
Symptoms of Overdose:
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Fluid Overload (Swelling, Breathing Difficulty)
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High Blood Pressure
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Heart Failure Symptoms (Chest Pain, Rapid Heartbeat)
What to Do in Case of Overdose?
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Stop infusion immediately.
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Seek emergency medical help.
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Diuretics may be given to remove excess fluid.
Missed Dose Instructions
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Not applicable, as it is administered in hospitals.
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If a scheduled dose is missed, it should be given as soon as possible.