Product Introduction:
Capiibine 500mg is a widely used oral chemotherapy medication for treating various types of cancer, either alone or in combination with other drugs. It helps shrink tumors, slow cancer progression, and improve survival rates in patients with metastatic and early-stage cancers.
Uses of Capiibine 500mg
Capiibine 500mg is primarily used to treat:
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Metastatic Colorectal Cancer – First-line therapy or combination treatment.
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Metastatic Breast Cancer – Often combined with Docetaxel for advanced cases.
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Gastric (Stomach) Cancer – Used alone or with platinum-based chemotherapy.
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Esophageal Cancer – Helps shrink tumors before surgery.
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Pancreatic Cancer – Used in some off-label cases.
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Adjuvant Therapy – Prevents cancer recurrence after surgery.
How Capiibine 500mg Works (Mechanism of Action):
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Capecitabine is a prodrug – It converts into 5-Fluorouracil (5-FU) inside the body.
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5-FU disrupts DNA & RNA synthesis in cancer cells.
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This stops cancer cell growth and leads to tumor shrinkage and cell death.
✅ It selectively targets cancer cells while minimizing damage to normal tissues.
Dosage of Capiibine 500mg
Typical Recommended Dose:
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Colorectal Cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day break.
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Breast Cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day break (often combined with Docetaxel).
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Stomach Cancer: 1,250 mg/m² twice daily for 14 days, followed by a 7-day break.
⚠️ Dosage is based on body weight, kidney function, and doctor’s prescription.
Method of Administration (How to Take It)
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Take Capiibine 500mg within 30 minutes after a meal with water.
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Swallow the tablet whole (Do not crush or chew).
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Follow the prescribed schedule (14-day treatment + 7-day break cycle).
Side Effects of Capiibine 500mg
Common Side Effects:
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Hand-Foot Syndrome (Redness, peeling, and pain in hands & feet)
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Nausea, Vomiting, and Diarrhea
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Fatigue & Weakness
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Loss of Appetite & Weight Loss
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Mouth Sores & Dry Mouth
Severe Side Effects (Seek Immediate Medical Help):
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Severe diarrhea & dehydration
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Irregular heartbeat or chest pain
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Liver toxicity (Yellowing of skin, dark urine)
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Severe hand-foot syndrome (blisters, ulcers, swelling)
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Low white blood cell count (Increased infection risk)
🚨 If severe symptoms occur, contact a doctor immediately.
Precautions Before Taking Capiibine 500mg
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Kidney or Liver Disease: Dose adjustments may be required.
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Heart Problems: May cause irregular heartbeat.
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Pregnancy & Breastfeeding: Not safe – Can harm the fetus.
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Diabetes: Monitor blood sugar levels closely.
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Dehydration Risk: Stay hydrated to avoid severe diarrhea.
Drug Interactions (Medications That May Interact)
Capiibine 500mg may interact with:
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Warfarin & Blood Thinners: Increases bleeding risk.
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Phenytoin (Seizure Medication): Increases phenytoin toxicity.
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Leucovorin (Folic Acid): Increases Capecitabine toxicity.
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Antacids (Magnesium, Aluminum Hydroxide): May affect drug absorption.
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Live Vaccines: Avoid while on chemotherapy.
⚠️ Always inform your doctor about all medications you are taking.
Allergy Warnings
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Do not take if allergic to Capecitabine or Fluorouracil (5-FU).
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Symptoms of an allergic reaction:
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Swelling, Rash, Itching
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Shortness of breath, Chest tightness
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Severe dizziness
🚨 Seek emergency medical help if allergic symptoms occur.
Storage Instructions
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Store at room temperature (20°C - 25°C).
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Keep away from moisture and direct sunlight.
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Store in the original packaging.
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Keep out of reach of children.
Overdose Information
Symptoms of Overdose:
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Severe diarrhea & vomiting
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Severe hand-foot syndrome
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Extreme fatigue & confusion
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Irregular heartbeat
What to Do in Case of Overdose?
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Seek emergency medical help immediately.
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Hospitalization may be required for supportive treatment.
Missed Dose Instructions
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If a dose is missed, take it as soon as possible.
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If it’s close to the next dose, skip the missed dose.
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Do not double the dose to make up for a missed one.
