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Lenmid 10mg - Lenalidomide Capsules

Lenmid 10mg contains Lenalidomide, an immunomodulatory drug used primarily in the treatment of blood cancers such as multiple myeloma and myelodysplastic syndromes. It helps to slow the growth of cancer cells and boost the immune response.

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General Information:
Generic Name: Lenalidomide
Brand Name: Lenmid 10mg
Packing: 10 Capsules in Bottle
Strength: 10 mg
Manufacturer: Cipla Ltd.
Form: Oral Capsules
Category: Anti-cancer / Immunomodulatory Agent
Product Introduction:
Lenmid 10mg is a prescription medication used to treat various hematological cancers. It is most commonly used in combination with other therapies or as a monotherapy for specific cancer types. Manufactured with strict quality standards, Lenmid is widely used in oncology across the globe.

Uses:
Lenmid 10mg is used for the treatment of:
  1. Multiple Myeloma – in combination with dexamethasone or other agents.
  2. Myelodysplastic Syndromes (MDS) – particularly those with chromosome 5q deletion.
  3. Mantle Cell Lymphoma (MCL) – in patients who have relapsed or become resistant to other treatments.
  4. Follicular Lymphoma – when used as a second-line or later treatment.
  5. Chronic Lymphocytic Leukemia (CLL) – under clinical guidance.
  6. Cutaneous T-cell Lymphoma (CTCL) – in selected cases where other treatments fail.

Storage Instructions:
  1. Store below 25°C.
  2. Keep in original packaging to protect from moisture.
  3. Keep out of reach of children.
  4. Do not use after the expiry date printed on the packaging.

How It Works (Mechanism of Action):
Lenalidomide works by modifying the immune system and inhibiting the growth of cancerous cells. It enhances T-cell and natural killer (NK) cell-mediated immunity, promotes apoptosis (programmed cell death) of cancer cells, and inhibits angiogenesis (formation of new blood vessels that supply tumors).

Side Effects:
Common side effects:
  1. Fatigue
  2. Diarrhea or constipation
  3. Rash
  4. Nausea
  5. Dizziness
  6. Low blood cell counts (anemia, neutropenia, thrombocytopenia)
Severe side effects:
  1. Blood clots (deep vein thrombosis, pulmonary embolism)
  2. Liver toxicity
  3. Severe skin reactions
  4. Tumor lysis syndrome
  5. Secondary cancers in rare cases
Seek immediate medical help if serious side effects occur.

Dosage (Typical Recommended Dose):
  1. The usual starting dose is 10 mg once daily, depending on the condition being treated.
  2. Dose may be adjusted based on patient response, kidney function, and tolerance.
  3. Treatment cycles may include 21 days on drug followed by 7 days off.

Method of Administration:
  1. Take the capsule orally with water. 
  2. Swallow whole, do not crush or chew.
  3. Can be taken with or without food.
  4. Follow the dosing schedule as prescribed by your oncologist.

Precautions:
  1. Not recommended during pregnancy; causes severe birth defects.
  2. Use effective contraception (both males and females) during and for several weeks after treatment.
  3. Regular blood tests are essential to monitor blood counts.
  4. Avoid if you have a history of blood clots unless prescribed with precautions.
  5. Inform your doctor if you have liver, kidney, or heart problems.

Drug Interactions:
Lenmid may interact with:
  1. Dexamethasone (increases risk of blood clots)
  2. Erythropoietin-stimulating agents
  3. Anticoagulants (warfarin, enoxaparin)
  4. Immunosuppressants
  5. Other chemotherapy drugs
  6. Hormonal therapies
Always inform your doctor of all medications and supplements you're taking.

Aller gies:
  1. Do not use if allergic to Lenalidomide or any of its excipients.
  2. Symptoms of allergic reactions may include rash, itching, swelling, dizziness, or difficulty breathing.

 Overdose Information:
  1. In case of an overdose, seek emergency medical help immediately.
  2. Symptoms may include severe dizziness, fainting, or extreme fatigue.
  3. There is no specific antidote; treatment is supportive and symptom-based.

Missed Dose Instructions:
  1. If you miss a dose and it’s less than 12 hours late, take it as soon as remembered.
  2. If more than 12 hours late, skip the missed dose and resume your regular schedule.
  3. Do not double the dose to make up for a missed one.

Additional Notes:
  1. This medication is part of a Risk Evaluation and Mitigation Strategy (REMS) program in some countries due to its teratogenic effects.
  2. Handle capsules with care; avoid opening or crushing them.
  3. Periodic monitoring for blood counts and organ function is necessary.
  4. Patients should carry identification stating they are on Lenalidomide therapy.
  5. Avoid activities requiring alertness (e.g., driving) until you know how the drug affects you.
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