Buy Vorier 200mg - Voriconazole Tablet Online, Vorier 200mg

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Vorier 200mg - Voriconazole Tablet

Vorier 200mg is a powerful antifungal medication used to treat serious fungal infections like invasive aspergillosis and candidemia. It belongs to the class of triazole antifungals and is often used in immunocompromised patients.

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Description Product Details

General Information:

Generic Name: Voriconazole

Brand Name: Vorier

Packing: Strip of tablets (typically 4 or 6 tablets per strip)

Strength: 200 mg

Manufacturer: Zydus Lifesciences

Form: Tablet

Category: Antifungal, Prescription-only medicine

Product Intro:

Vorier 200mg contains Voriconazole, a second-generation triazole antifungal, formulated for oral administration. It is especially effective against invasive fungal infections and is considered a first-line treatment in many severe fungal disease protocols.

Uses:

Invasive aspergillosis
Candidemia in non-neutropenic patients
Serious infections caused by Scedosporium apiospermum
Infections due to Fusarium species
Treatment of esophageal candidiasis
Prophylaxis in high-risk immunocompromised patients (e.g., bone marrow transplant recipients)

Storage Instructions:

Store at room temperature (15°C to 30°C)
Keep in a cool, dry place away from moisture
Protect from light and heat
Keep out of reach of children

How it Works (Mechanism of Action):

Voriconazole works by inhibiting the fungal cytochrome P450 enzyme 14α-demethylase, which is essential for ergosterol synthesis. Ergosterol is a vital component of the fungal cell membrane, and its disruption leads to increased cell permeability and fungal cell death.

Side Effects:

Common Side Effects:

Visual disturbances (blurred vision, photophobia)
Nausea and vomiting
Rash
Headache
Fever
Diarrhea

Severe Side Effects:

Hepatotoxicity (elevated liver enzymes)
QT interval prolongation (heart rhythm abnormalities)
Skin reactions, including Stevens-Johnson Syndrome
Hallucinations or confusion
Photosensitivity and risk of skin cancer with long-term use

Dosage (Typical Recommended Dose):

Loading dose (Day 1): 400 mg every 12 hours
Maintenance dose (from Day 2 onward): 200 mg every 12 hours
Dose may vary based on weight, liver function, or co-administered medications
Always take under physician supervision

Method of Administration:

Take orally with or without food (though best on an empty stomach)
Swallow the tablet whole with a glass of water
Maintain consistent timing between doses
Do not crush or chew

Precautions:

Monitor liver function tests (LFTs) during treatment
Use with caution in patients with pre-existing cardiac arrhythmias
Avoid exposure to direct sunlight; wear sunscreen and protective clothing
Not recommended in pregnancy or breastfeeding
Patients should avoid driving or operating machinery if visual disturbances occur

Drug Interactions:

Avoid with rifampicin, carbamazepine, phenobarbital (reduces efficacy)
May increase levels of cyclosporine, tacrolimus, sirolimus (monitor levels closely)
Interacts with statins, warfarin, omeprazole
Do not take with St. John’s Wort

Allergies:

Contraindicated in patients with known hypersensitivity to Voriconazole
Symptoms of allergic reaction: rash, swelling, itching, trouble breathing

Overdose Information:

Overdose may lead to hallucinations, confusion, abnormal liver tests
Seek emergency medical attention immediately
Symptomatic and supportive care is recommended

Missed Dose Instructions:

Take the missed dose as soon as possible
If it’s near the time of the next dose, skip the missed dose
Do not double up to make up for the missed one

Additional Notes:

Routine eye exams may be needed for patients on long-term therapy
Monitor electrolytes (especially potassium and magnesium)
Use the medicine exactly as prescribed to prevent antifungal resistance
Avoid alcohol during the course of therapy