0
₹0 0
Nextgen Biotech

Call us:

menu

Renocrit 10000iu - Erythropoietin Injection

  • Home
  • Renocrit 10000iu - Erythropoietin Injection

Renocrit 10000iu - Erythropoietin Injection

Renocrit 10000 IU is a recombinant human erythropoietin alfa injection used to treat anemia, especially in patients with chronic kidney disease or those undergoing chemotherapy. It helps stimulate red blood cell production and reduce the need for blood transfusions.

Choose Quantity:

-
+
+ Add To Cart
Add to wishlist
Share
Description Product Details
General Information:
Generic Name: Erythropoietin Alfa
Brand Name: Renocrit
Packing: Prefilled syringe or single-use vial
Strength: 10000 IU per 1 ml
Manufacturer: Intas Pharmaceuticals Ltd.
Form: Injection (solution for injection)
Category: Anti-anemic / Hematopoietic Growth Factor
Product Intro:
Renocrit 10000 IU is a high-dose formulation of erythropoietin alfa, developed by Intas Pharmaceuticals, designed to manage severe anemia caused by chronic illnesses. By boosting red blood cell production, it helps improve energy, oxygen delivery, and overall well-being in anemic patients.
Uses:
  1. Anemia in Chronic Kidney Disease (CKD) – including dialysis and non-dialysis patients
  2. Chemotherapy-induced Anemia – to reduce transfusion need
  3. HIV-associated anemia – particularly with zidovudine therapy
  4. Anemia in bone marrow disorders – such as myelodysplastic syndromes
  5. Anemia before elective surgery – to minimize blood transfusion
  6. Anemia in premature infants or critical care patients (as determined by a physician)
Storage Instructions:
  1. Store in a refrigerator between 2°C to 8°C
  2. Do not freeze
  3. Protect from light and heat
  4. Do not shake the vial/syringe
  5. Bring to room temperature before injection
How it Works (Mechanism of Action):
Renocrit contains recombinant erythropoietin alfa that mimics the body’s natural erythropoietin hormone. It binds to erythropoietin receptors on bone marrow progenitor cells, stimulating the production and maturation of red blood cells, thereby improving oxygen transport in the body.
Side Effects:
Common Side Effects:
  1. Pain or redness at injection site
  2. Headache
  3. Fever
  4. Body aches
  5. Nausea
Severe Side Effects:
  1. Hypertension (high blood pressure)
  2. Thrombotic events (clots, strokes)
  3. Seizures
  4. Pure Red Cell Aplasia (PRCA) – a rare immune reaction
  5. Serious allergic reactions – such as rash, swelling, breathing difficulty
Dosage (Typical Recommended Dose):
  1. Dialysis patients: 50–100 IU/kg IV or SC, 3 times per week
  2. Non-dialysis CKD patients: 75–150 IU/kg SC, once or twice a week
  3. Cancer-related anemia: 150 IU/kg SC 3 times/week or 40,000 IU once/week
  4. Dosage is adjusted based on hemoglobin response and patient condition
Method of Administration:
  1. Given by subcutaneous (SC) or intravenous (IV) injection
  2. Should be administered by a healthcare professional or trained caregiver
  3. Rotate injection sites to avoid skin irritation
  4. Inspect solution for any discoloration or particles before use
Precautions:
  1. Monitor hemoglobin and blood pressure regularly
  2. Avoid hemoglobin >12 g/dL to reduce risk of cardiovascular issues
  3. Ensure adequate iron levels – supplementation may be needed
  4. Use cautiously in patients with history of seizures, heart disease, or thrombosis
  5. Discontinue if PRCA is suspected
Drug Interactions:
  1. Iron supplements – often co-administered
  2. Antihypertensive medications – monitor BP carefully
  3. No major drug-drug interactions reported, but monitor in polypharmacy cases
Allergies:
  1. Contraindicated in individuals with known hypersensitivity to erythropoietin or formulation components
  2. Allergic reactions can include:
    1. Skin rash or itching
    2. Facial swelling
    3. Difficulty breathing
    4. Anaphylaxis (in rare cases)
Overdose Information:
  1. Symptoms: Excessive hemoglobin, hypertension, or risk of clot formation
  2. Management: Discontinue therapy, monitor vitals, consider phlebotomy in severe cases
  3. Seek immediate medical attention in suspected overdose
Missed Dose Instructions:
  1. Take the missed dose as soon as you remember
  2. If it is close to your next dose, skip the missed one
  3. Do not double the dose to make up for the missed one
Additional Notes:
  1. Full benefits may take several weeks to be noticeable
  2. Regular lab monitoring is essential during therapy
  3. Inform your healthcare provider of any new symptoms, persistent fatigue, or shortness of breath
  4. Lifestyle factors like smoking or poor nutrition may impact effectiveness
View More

In The Same Category

Cart