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Vintor 4000mg - Erythropoietin Injection

Vintor 4000 IU is a recombinant human erythropoietin injection used to treat anemia in patients with chronic kidney disease, cancer undergoing chemotherapy, or HIV therapy. It helps stimulate red blood cell production, improving oxygen transport in the body.

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General Information:
Generic Name: Erythropoietin
Brand Name: Vintor
Packing: Pre-filled syringe or vial
Strength: 4000 IU
Manufacturer: Gennova Biopharmaceuticals
Form: Injectable solution
Category: Hematinic / Anti-anemic
Product Intro:
Vintor 4000 IU is a synthetic erythropoietin alpha formulation designed to effectively manage anemia. Manufactured by Gennova Biopharmaceuticals, it plays a key role in supporting patients with reduced red blood cell counts due to medical conditions or treatments like dialysis and chemotherapy.

Uses:
  1. Anemia due to chronic kidney disease (CKD)
  2. Anemia in cancer patients undergoing chemotherapy
  3. Anemia associated with HIV therapy (especially with zidovudine)
  4. Anemia in patients undergoing major surgery to reduce need for blood transfusions
  5. Anemia following bone marrow or stem cell transplants
  6. Anemia caused by myelodysplastic syndromes

Storage Instructions:
  1. Store at 2°C to 8°C (refrigerated)
  2. Do not freeze or expose to sunlight
  3. Do not shake the syringe or vial
  4. Keep away from children and pets

How it Works (Mechanism of Action):
Vintor mimics the natural hormone erythropoietin, which is normally produced by the kidneys. It stimulates the bone marrow to increase the production of red blood cells, helping alleviate symptoms of anemia like fatigue and weakness.

Side Effects:
Common Side Effects:
  1. Fever
  2. Headache
  3. Dizziness
  4. Nausea
  5. Injection site redness or pain
  6. High blood pressure
Severe Side Effects:
  1. Blood clots
  2. Stroke or heart attack (rare, in case of overcorrection)
  3. Seizures
  4. Pure red cell aplasia (PRCA)
  5. Allergic reactions (anaphylaxis)

Dosage (Typical Recommended Dose):
  1. 4000 IU, typically given 2-3 times per week depending on patient’s condition and physician guidance
  2. Dosage may be adjusted based on hemoglobin response
  3. Regular monitoring is advised during treatment

Method of Administration:
  1. Administered either subcutaneously (SC) or intravenously (IV)
  2. Injection should be performed by a healthcare provider or trained caregiver
  3. Rotate injection sites if SC
  4. Let the solution reach room temperature before injection

Precautions:
  1. Monitor blood pressure and hemoglobin regularly
  2. Avoid in patients with uncontrolled hypertension
  3. Use with caution in patients with seizure disorders or cardiovascular disease
  4. Check for iron, folate, or vitamin B12 deficiencies and supplement as needed
  5. Not advised for patients with a history of PRCA due to erythropoietin

Drug Interactions:
  1. No major drug interactions, but inform your doctor about:
    1. Chemotherapy agents
    2. Antihypertensives
    3. Iron supplements (can enhance effectiveness)

Allergies:
  1. Contraindicated in patients allergic to erythropoietin or excipients in formulation
  2. Watch for signs of allergy: hives, swelling, shortness of breath
  3. Discontinue immediately if an allergic reaction occurs

Overdose Information:
  1. Overdose may cause excessive erythrocytosis, leading to blood clots, stroke, or hypertension
  2. Seek immediate medical attention
  3. Management involves withholding the drug and symptomatic treatment

Missed Dose Instructions:
  1. Take the missed dose as soon as remembered
  2. If it's close to the next scheduled dose, skip the missed one
  3. Never double the dose to catch up

Additional Notes:
  1. Regular monitoring is critical for safe and effective use
  2. Often combined with iron supplementation
  3. Adjust dose gradually to avoid rapid hemoglobin increase
  4. Should only be used under medical supervision
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