Buy Temotero 100mg - Temozolomide Capsules Online, Temotero 100mg

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Temotero 100mg - Temozolomide Capsules

Temotero 100mg is an oral chemotherapy medication used to treat brain cancers such as glioblastoma multiforme and anaplastic astrocytoma. It belongs to the alkylating agents class and interferes with the DNA of cancer cells, inhibiting their growth.

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Description Product Details

General Information:

Generic Name: Temozolomide

Brand Name: Temotero

Packing: 1 x 5 Capsules

Strength: 100 mg

Manufacturer: Hetero Healthcare Ltd.

Form: Capsule

Category: Anticancer / Chemotherapy / Alkylating Agent

Product Intro:

Temotero 100mg contains Temozolomide, a potent alkylating agent used in the treatment of brain tumors. It is commonly administered in combination with radiation therapy or as part of maintenance therapy in adult patients.

Uses:

Treatment of glioblastoma multiforme (GBM)
Management of anaplastic astrocytoma
Used concurrently with radiotherapy for brain tumors
Maintenance therapy post-radiation treatment
Off-label use in metastatic melanoma (under strict supervision)
Investigational use in pediatric brain tumors

Storage Instructions:

Store in a cool and dry place below 25°C
Protect from moisture and light
Do not freeze
Keep away from children and pets

How it Works (Mechanism of Action):

Temozolomide is a DNA-alkylating agent that is converted in the body to its active form, MTIC. MTIC methylates DNA at guanine residues, which damages the DNA and leads to the death of rapidly dividing tumor cells through apoptosis.

Side Effects:

Common Side Effects:

Nausea and vomiting
Fatigue
Headache
Diarrhea or constipation
Anorexia
Hair loss or thinning

Severe Side Effects:

Myelosuppression (anemia, neutropenia, thrombocytopenia)
Hepatotoxicity
Severe infections (due to low immunity)
Rare allergic reactions
Secondary cancers with long-term use

Dosage (Typical Recommended Dose):

Standard dosing is based on body surface area (BSA)
During radiotherapy: 75 mg/m² daily
Maintenance therapy: 150–200 mg/m²/day for 5 days in a 28-day cycle
The 100mg capsule allows for flexible dose adjustments, especially in combination with 20mg, 250mg capsules, etc.

Method of Administration:

Take orally on an empty stomach (1 hour before or 2 hours after food)
Swallow whole with water; do not crush or chew
Take at the same time daily for consistency
Use gloves or wash hands after handling the capsule

Precautions:

Regular blood tests needed to monitor blood counts
Avoid in pregnant and breastfeeding women
Use effective contraception during and for at least 6 months after therapy
Avoid live vaccines during treatment
Caution in patients with liver or kidney impairment

Drug Interactions:

Increased risk of toxicity with other chemotherapy agents
Interacts with phenytoin, warfarin, and steroids
Avoid alcohol as it may increase liver toxicity
Avoid herbal supplements unless cleared by a doctor

Allergies:

Not suitable for patients with allergy to Temozolomide or Dacarbazine
Symptoms may include skin rash, itching, swelling, dizziness, or breathing issues

Overdose Information:

Symptoms include severe myelosuppression, fatigue, and increased infection risk
Seek emergency medical attention
Hospitalization may be required; no specific antidote available

Missed Dose Instructions:

Take the missed dose as soon as you remember on the same day
Do not double the dose next day
If it's near the next dose, skip the missed one and continue regularly

Additional Notes:

Regular monitoring of CBC, liver function, and renal function is crucial
Always consult a doctor before dose changes
Avoid unnecessary exposure to crowds or people with infections
Inform your doctor of any ongoing medications or supplements