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Imatero 100mg - Imatinib Tablet

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Imatero 100mg - Imatinib Tablet

Imatero 100mg is a targeted chemotherapy medicine that contains Imatinib, designed to treat blood cancers like CML and ALL, and other tumors. It works by blocking specific proteins responsible for cancer cell growth.

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Description Product Details
General Information:
Generic Name: Imatinib
Brand Name: Imatero 100mg
Packing: Strip of 10 Tablets
Strength: 100mg
Manufacturer: Hetro Healthcare Limited
Form: Tablet
Category: Anticancer / Tyrosine Kinase Inhibitor
Product Intro:
Imatero 100mg is an oral anticancer medication formulated with Imatinib, a tyrosine kinase inhibitor. It is especially effective in treating certain leukemias and tumors by targeting and inhibiting cancer-causing proteins at the cellular level.
Uses:
Imatero 100mg is used in the treatment of:
  1. Chronic Myeloid Leukemia (CML)
  2. Acute Lymphoblastic Leukemia (ALL) – Philadelphia chromosome-positive
  3. Gastrointestinal Stromal Tumors (GIST)
  4. Dermatofibrosarcoma Protuberans (DFSP)
  5. Hypereosinophilic Syndrome (HES)
  6. Chronic Eosinophilic Leukemia (CEL)
Storage Instructions:
  1. Store below 30°C in a cool and dry place
  2. Keep away from moisture and direct sunlight
  3. Store out of reach of children
How it Works (Mechanism of Action):
Imatinib inhibits BCR-ABL tyrosine kinase, an abnormal enzyme produced in leukemia cells. By blocking this enzyme, it prevents the growth and multiplication of cancer cells, leading to their death and improved patient outcomes.
Side Effects:
Common Side Effects:
  1. Fluid retention (especially around the eyes)
  2. Nausea and vomiting
  3. Fatigue
  4. Muscle cramps
  5. Rash
  6. Diarrhea
Severe Side Effects:
  1. Liver dysfunction
  2. Bone marrow suppression (anemia, neutropenia, thrombocytopenia)
  3. Heart complications
  4. Severe skin reactions
  5. Gastrointestinal bleeding
Dosage (Typical Recommended Dose):
  1. For CML: Usually 400mg daily in adults, divided doses like Imatero 100mg can be used as per prescription
  2. For pediatric patients: Dosage is based on body weight/body surface area
  3. Always follow the physician’s exact dosage recommendation
Method of Administration:
  1. Administer orally with water
  2. Take with food to reduce stomach upset
  3. Swallow tablets whole—do not crush or chew
Precautions:
  1. Regular monitoring of blood counts and liver function is essential
  2. Use cautiously in patients with liver, kidney, or heart disorders
  3. Not recommended during pregnancy or lactation unless necessary
  4. Patients should avoid activities requiring alertness if experiencing dizziness
Drug Interactions:
  1. CYP3A4 inhibitors (e.g., clarithromycin) may increase Imatinib levels
  2. CYP3A4 inducers (e.g., rifampicin) can reduce effectiveness
  3. Interacts with warfarin, phenytoin, and St. John's wort
  4. Avoid grapefruit juice, which can alter drug metabolism
Allergies:
  1. Contraindicated in patients with hypersensitivity to Imatinib or excipients
  2. Seek immediate medical help if symptoms like rash, itching, or swelling appear
Overdose Information:
  1. Symptoms may include nausea, vomiting, fluid retention, and low blood counts
  2. In case of overdose, seek emergency medical assistance immediately
Missed Dose Instructions:
  1. If you miss a dose, take it as soon as you remember
  2. If it’s almost time for your next dose, skip the missed one
  3. Do not double dose to compensate
Additional Notes:
  1. Ensure good hydration during treatment
  2. Regular blood tests are crucial to monitor drug efficacy and safety
  3. Inform your doctor of all supplements or OTC drugs being used
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