Product Introduction:
Lenmid 25mg is a high-strength oral capsule prescribed for cancer treatment, especially in hematological malignancies. It is usually part of a combination therapy and has shown improved patient survival when administered under medical supervision. This medicine is manufactured by Cipla Ltd, a trusted name in pharmaceutical manufacturing.
Uses:
Lenmid 25mg is used to treat several types of blood and lymphatic cancers, including:
-
Multiple Myeloma – often in combination with dexamethasone or other therapies.
-
Myelodysplastic Syndromes (MDS) – particularly in patients with 5q chromosomal deletion.
-
Mantle Cell Lymphoma (MCL) – especially in relapsed or refractory cases.
-
Chronic Lymphocytic Leukemia (CLL) – as a second-line treatment.
-
Follicular Lymphoma – off-label or clinical use.
-
Cutaneous T-cell Lymphoma (CTCL) – under specific clinical circumstances.
Storage Instructions:
-
Store at room temperature, below 25°C.
-
Keep away from moisture, heat, and direct sunlight.
-
Store in the original container.
-
Keep out of reach of children and pets.
How It Works (Mechanism of Action):
Lenalidomide, the active ingredient in Lenmid 25mg, works through multiple mechanisms:
-
Enhances immune system activity by stimulating T cells and NK cells.
-
Inhibits the formation of new blood vessels (anti-angiogenesis) that tumors need to grow.
-
Suppresses the proliferation of abnormal cells.
-
Promotes apoptosis (programmed cell death) of malignant cells.
-
Alters cytokine production and microenvironment in the bone marrow, reducing disease progression.
Side Effects:
Common side effects:
-
Fatigue
-
Constipation or diarrhea
-
Dizziness
-
Muscle cramps
-
Nausea and vomiting
-
Low white blood cell or platelet counts
Severe side effects:
-
Blood clots (DVT, PE)
-
Liver function abnormalities
-
Secondary cancers (rare)
-
Tumor lysis syndrome
-
Serious skin reactions (Stevens-Johnson syndrome)
-
Severe allergic reactions
Seek immediate medical attention if experiencing severe symptoms.
Dosage (Typical Recommended Dose):
-
The usual adult dose for multiple myeloma is 25 mg once daily on Days 1–21 of a 28-day treatment cycle.
-
Dosage may vary based on kidney function, treatment phase, and patient tolerance.
-
Dosage adjustments are common and must be made under the supervision of a physician.
Method of Administration:
-
Take orally with a glass of water.
-
Swallow the capsule whole—do not open, crush, or chew.
-
Can be taken with or without food.
-
Stick strictly to the dosing schedule provided by your healthcare provider.
Precautions:
-
Pregnancy warning: Extremely teratogenic. Use of effective birth control is mandatory for both male and female patients.
-
Patients must avoid donating blood or sperm during treatment and for a specified period after discontinuation.
-
Regular blood tests are needed to monitor blood cell counts and organ functions.
-
Use with caution in patients with a history of thromboembolism, liver/kidney disorders, or neuropathy.
-
Avoid alcohol and other drugs that may suppress bone marrow function.
Drug Interactions:
Potential drug interactions include:
-
Dexamethasone (increased clotting risk)
-
Erythropoietin-stimulating agents
-
Anticoagulants (e.g., warfarin, heparin)
-
Other immunosuppressants or chemotherapeutics
-
Live vaccines – should be avoided
Always inform your doctor about all medications, herbs, or supplements you’re using.
Allergies:
-
Do not take Lenmid 25mg if allergic to Lenalidomide or any of the capsule’s components.
-
Signs of an allergic reaction include hives, rash, itching, swelling (especially of the face/tongue), and difficulty breathing.
-
Discontinue use and seek emergency help if an allergic reaction occurs.
Overdose Information:
-
In case of accidental overdose, seek emergency medical attention.
-
Overdose symptoms may include extreme fatigue, confusion, dizziness, or abnormal bleeding.
-
There is no specific antidote; treatment is supportive with symptomatic management.
Missed Dose Instructions:
-
If you miss a dose and remember within 12 hours, take it as soon as possible.
-
If more than 12 hours have passed, skip the missed dose and continue your regular schedule.
-
Do not take a double dose to make up for the missed one.
Additional Notes:
-
Patients receiving Lenalidomide must be enrolled in a controlled distribution program (e.g., REMS in the US).
-
Periodic monitoring (CBC, liver/kidney function tests) is essential.
-
Be cautious while driving or using machinery until you know how the medicine affects you.
-
Patients should always carry an ID card stating they are on Lenalidomide therapy.
-
Use gloves when handling the capsule, especially by caregivers or family members.
Product Introduction:
Lenmid 25mg is a high-strength oral capsule prescribed for cancer treatment, especially in hematological malignancies. It is usually part of a combination therapy and has shown improved patient survival when administered under medical supervision. This medicine is manufactured by Cipla Ltd, a trusted name in pharmaceutical manufacturing.
Uses:
Lenmid 25mg is used to treat several types of blood and lymphatic cancers, including:
-
Multiple Myeloma – often in combination with dexamethasone or other therapies.
-
Myelodysplastic Syndromes (MDS) – particularly in patients with 5q chromosomal deletion.
-
Mantle Cell Lymphoma (MCL) – especially in relapsed or refractory cases.
-
Chronic Lymphocytic Leukemia (CLL) – as a second-line treatment.
-
Follicular Lymphoma – off-label or clinical use.
-
Cutaneous T-cell Lymphoma (CTCL) – under specific clinical circumstances.
Storage Instructions:
-
Store at room temperature, below 25°C.
-
Keep away from moisture, heat, and direct sunlight.
-
Store in the original container.
-
Keep out of reach of children and pets.
How It Works (Mechanism of Action):
Lenalidomide, the active ingredient in Lenmid 25mg, works through multiple mechanisms:
-
Enhances immune system activity by stimulating T cells and NK cells.
-
Inhibits the formation of new blood vessels (anti-angiogenesis) that tumors need to grow.
-
Suppresses the proliferation of abnormal cells.
-
Promotes apoptosis (programmed cell death) of malignant cells.
-
Alters cytokine production and microenvironment in the bone marrow, reducing disease progression.
Side Effects:
Common side effects:
-
Fatigue
-
Constipation or diarrhea
-
Dizziness
-
Muscle cramps
-
Nausea and vomiting
-
Low white blood cell or platelet counts
Severe side effects:
-
Blood clots (DVT, PE)
-
Liver function abnormalities
-
Secondary cancers (rare)
-
Tumor lysis syndrome
-
Serious skin reactions (Stevens-Johnson syndrome)
-
Severe allergic reactions
Seek immediate medical attention if experiencing severe symptoms.
Dosage (Typical Recommended Dose):
-
The usual adult dose for multiple myeloma is 25 mg once daily on Days 1–21 of a 28-day treatment cycle.
-
Dosage may vary based on kidney function, treatment phase, and patient tolerance.
-
Dosage adjustments are common and must be made under the supervision of a physician.
Method of Administration:
-
Take orally with a glass of water.
-
Swallow the capsule whole—do not open, crush, or chew.
-
Can be taken with or without food.
-
Stick strictly to the dosing schedule provided by your healthcare provider.
Precautions:
-
Pregnancy warning: Extremely teratogenic. Use of effective birth control is mandatory for both male and female patients.
-
Patients must avoid donating blood or sperm during treatment and for a specified period after discontinuation.
-
Regular blood tests are needed to monitor blood cell counts and organ functions.
-
Use with caution in patients with a history of thromboembolism, liver/kidney disorders, or neuropathy.
-
Avoid alcohol and other drugs that may suppress bone marrow function.
Drug Interactions:
Potential drug interactions include:
-
Dexamethasone (increased clotting risk)
-
Erythropoietin-stimulating agents
-
Anticoagulants (e.g., warfarin, heparin)
-
Other immunosuppressants or chemotherapeutics
-
Live vaccines – should be avoided
Always inform your doctor about all medications, herbs, or supplements you’re using.
Allergies:
-
Do not take Lenmid 25mg if allergic to Lenalidomide or any of the capsule’s components.
-
Signs of an allergic reaction include hives, rash, itching, swelling (especially of the face/tongue), and difficulty breathing.
-
Discontinue use and seek emergency help if an allergic reaction occurs.
Overdose Information:
-
In case of accidental overdose, seek emergency medical attention.
-
Overdose symptoms may include extreme fatigue, confusion, dizziness, or abnormal bleeding.
-
There is no specific antidote; treatment is supportive with symptomatic management.
Missed Dose Instructions:
-
If you miss a dose and remember within 12 hours, take it as soon as possible.
-
If more than 12 hours have passed, skip the missed dose and continue your regular schedule.
-
Do not take a double dose to make up for the missed one.
Additional Notes:
-
Patients receiving Lenalidomide must be enrolled in a controlled distribution program (e.g., REMS in the US).
-
Periodic monitoring (CBC, liver/kidney function tests) is essential.
-
Be cautious while driving or using machinery until you know how the medicine affects you.
-
Patients should always carry an ID card stating they are on Lenalidomide therapy.
-
Use gloves when handling the capsule, especially by caregivers or family members.