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Imatib 100mg - Imatinib Tablet

Imatib 100mg is an anti-cancer medicine used primarily to treat various forms of leukemia and certain tumors. It works by targeting abnormal proteins in cancer cells and halting their growth and spread.

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General Information:
Generic Name: Imatinib
Brand Name: Imatib 100mg
Packing: Strip of 10 tablets
Strength: 100mg
Manufacturer: Cipla Ltd.
Form: Tablet
Category: Anticancer / Tyrosine Kinase Inhibitor
Product Intro:
Imatib 100mg is a targeted therapy containing Imatinib, a tyrosine kinase inhibitor. It is widely prescribed for chronic myeloid leukemia and other cancers due to its effectiveness in blocking abnormal cell signaling pathways that cause cancer progression.

Uses:
Imatib 100mg is prescribed for the treatment of:
  1. Chronic Myeloid Leukemia (CML)
  2. Acute Lymphoblastic Leukemia (ALL) with Philadelphia chromosome
  3. Gastrointestinal Stromal Tumors (GIST)
  4. Hypereosinophilic Syndrome (HES)
  5. Chronic Eosinophilic Leukemia (CEL)
  6. Dermatofibrosarcoma Protuberans (DFSP)

Storage Instructions:
  1. Store in a dry place below 30°C
  2. Keep the tablets in the original packaging
  3. Protect from light and moisture
  4. Keep out of reach of children

How it Works (Mechanism of Action):
Imatinib targets specific proteins such as BCR-ABL tyrosine kinase produced by abnormal chromosomes in certain cancer cells. By inhibiting these proteins, it blocks the growth signal in cancer cells, causing them to stop growing or die.

Side Effects:
Common Side Effects:
  1. Nausea
  2. Vomiting
  3. Muscle cramps
  4. Rash or skin irritation
  5. Fatigue
  6. Diarrhea
Serious Side Effects:
  1. Liver toxicity
  2. Heart issues (such as fluid around the heart)
  3. Bone marrow suppression
  4. Severe skin reactions
  5. Bleeding or bruising easily

Dosage (Typical Recommended Dose):
  1. Adults (CML): Usually 400mg daily; Imatib 100mg can be used in divided doses as per prescription
  2. Children: Based on body surface area
  3. Always follow physician guidance for individual dose

Method of Administration:
  1. Take orally with a full glass of water
  2. Best taken with food to reduce gastrointestinal upset
  3. Do not crush or chew the tablet

Precautions:
  1. Regular blood tests are essential to monitor blood counts and liver function
  2. Use with caution in patients with liver, kidney, or heart conditions
  3. Not advised during pregnancy or breastfeeding unless clearly indicated
  4. Avoid driving or operating machinery if dizziness occurs

Drug Interactions:
  1. Avoid with CYP3A4 inducers/inhibitors like rifampin, ketoconazole
  2. May interact with warfarin, phenytoin, or St. John's Wort
  3. Avoid grapefruit juice, which can alter drug metabolism

Allergies:
  1. Avoid if allergic to Imatinib or any tablet ingredient
  2. Seek immediate medical help if you experience rash, itching, swelling, or difficulty breathing

Overdose Information:
  1. Symptoms may include nausea, vomiting, swelling, and low blood counts
  2. In case of overdose, go to the nearest emergency center immediately

Missed Dose Instructions:
  1. Take the missed dose as soon as you remember
  2. Skip the missed dose if it's near your next scheduled dose
  3. Do not double the dose to make up for the missed one

Additional Notes:
  1. Regular follow-ups are crucial to monitor the response
  2. Maintain hydration unless restricted
  3. Inform your healthcare provider about all medications and supplements you are taking
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