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Prolia 60mg is a Denosumab injection used for osteoporosis treatment and bone loss prevention in postmenopausal women and men at high risk of fractures. It works by blocking RANK Ligand (RANKL), a protein responsible for bone breakdown, enhancing bone density and reducing fracture risks. Prolia 60mg is a Denosumab injection used for osteoporosis treatment and bone loss prevention in postmenopausal women and men at high risk of fractures. It works by blocking RANK Ligand (RANKL), a protein responsible for bone breakdown, enhancing bone density and reducing fracture risks.
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Prolia 60mg is a prescription injection primarily used for osteoporosis in postmenopausal women and bone loss in men receiving hormone therapy for cancer. It helps to prevent fractures and maintain bone strength by reducing bone resorption. This drug is administered every six months via subcutaneous injection.
Prolia 60mg is prescribed for:
Postmenopausal Osteoporosis – Reduces fracture risks in women over 50 with low bone density.
Osteoporosis in Men – Improves bone strength in aging males with osteoporosis.
Bone Loss Due to Hormone Therapy in Cancer Patients – Prevents fractures in prostate and breast cancer patients undergoing hormonal therapy.
Glucocorticoid-Induced Osteoporosis – Used for osteoporosis caused by long-term steroid use.
Paget’s Disease of Bone (Off-label Use) – Helps in abnormal bone remodeling.
Store in a refrigerator (2°C – 8°C).
Do not freeze or expose to high temperatures.
Keep in original packaging to protect from light.
Before use, allow the injection to reach room temperature (about 30 minutes).
Do not shake the vial or syringe.
Denosumab is a RANK Ligand (RANKL) inhibitor that:
Prevents osteoclast activation – Inhibits the cells responsible for breaking down bone.
Slows bone loss and increases bone density – Maintains stronger bones by reducing bone resorption.
Reduces fracture risk – Helps prevent osteoporosis-related fractures in high-risk patients.
Low calcium levels (Hypocalcemia)
Back pain and joint pain
Fatigue and weakness
Skin rash or eczema
Flu-like symptoms
Mild swelling or redness at the injection site
Severe Hypocalcemia (muscle cramps, confusion, irregular heartbeat, seizures)
Osteonecrosis of the Jaw (ONJ) – A rare but serious condition causing jaw pain and delayed healing.
Atypical Bone Fractures – Unusual thigh bone fractures may occur.
Serious Infections – Increased risk of skin, urinary tract, or lung infections.
Severe Allergic Reactions – Swelling of the face, difficulty breathing, dizziness.
Seek immediate medical attention if any severe side effects occur.
60 mg every 6 months as a subcutaneous injection.
60 mg every 6 months to reduce the risk of fractures in patients undergoing hormone therapy.
Important:
Calcium and Vitamin D supplements are recommended during treatment.
Regular blood tests are required to monitor calcium levels.
Given subcutaneously (SC) in the upper arm, thigh, or abdomen.
Administered by a healthcare professional (self-administration is not recommended).
Before use, allow the injection to reach room temperature for 30 minutes.
Do not shake or dilute the solution.
Monitor calcium levels regularly to prevent hypocalcemia.
Dental check-ups are recommended to prevent jaw osteonecrosis.
Avoid invasive dental procedures while on treatment.
Not recommended in pregnancy or breastfeeding.
Patients with kidney disease require close monitoring due to increased risk of hypocalcemia.
Prolia 60mg may interact with:
Calcium & Vitamin D Supplements – Essential to reduce hypocalcemia risk.
Corticosteroids (Prednisone, Dexamethasone) – May worsen bone loss.
Chemotherapy & Immunosuppressants – Increases infection risk.
Bisphosphonates (Zoledronic Acid, Alendronate) – Avoid using together.
Live Vaccines – May reduce immune response.
Inform your doctor about all medications you are taking.
Do not use if allergic to Denosumab or any inactive ingredients.
Symptoms of an allergic reaction: rash, swelling, difficulty breathing, dizziness.
Seek emergency medical help if severe allergic reactions occur.
Severe low calcium levels (muscle spasms, confusion, seizures, irregular heartbeat)
Bone pain or unusual fractures
Severe fatigue or weakness
Seek immediate medical attention.
Treatment includes IV calcium supplementation and electrolyte monitoring.
If a dose is missed, take it as soon as possible.
Do not double the dose to compensate for a missed one.
Long delays in dosing may increase the risk of fractures.
Ensure adequate intake of calcium and vitamin D.
Regular dental check-ups are required to monitor for jaw problems.
Monitor kidney function if at risk of hypocalcemia.
Patients undergoing chemotherapy or radiation should consult their doctor before use.
Prolia 60mg is a prescription injection primarily used for osteoporosis in postmenopausal women and bone loss in men receiving hormone therapy for cancer. It helps to prevent fractures and maintain bone strength by reducing bone resorption. This drug is administered every six months via subcutaneous injection.
Prolia 60mg is prescribed for:
Postmenopausal Osteoporosis – Reduces fracture risks in women over 50 with low bone density.
Osteoporosis in Men – Improves bone strength in aging males with osteoporosis.
Bone Loss Due to Hormone Therapy in Cancer Patients – Prevents fractures in prostate and breast cancer patients undergoing hormonal therapy.
Glucocorticoid-Induced Osteoporosis – Used for osteoporosis caused by long-term steroid use.
Paget’s Disease of Bone (Off-label Use) – Helps in abnormal bone remodeling.
Store in a refrigerator (2°C – 8°C).
Do not freeze or expose to high temperatures.
Keep in original packaging to protect from light.
Before use, allow the injection to reach room temperature (about 30 minutes).
Do not shake the vial or syringe.
Denosumab is a RANK Ligand (RANKL) inhibitor that:
Prevents osteoclast activation – Inhibits the cells responsible for breaking down bone.
Slows bone loss and increases bone density – Maintains stronger bones by reducing bone resorption.
Reduces fracture risk – Helps prevent osteoporosis-related fractures in high-risk patients.
Low calcium levels (Hypocalcemia)
Back pain and joint pain
Fatigue and weakness
Skin rash or eczema
Flu-like symptoms
Mild swelling or redness at the injection site
Severe Hypocalcemia (muscle cramps, confusion, irregular heartbeat, seizures)
Osteonecrosis of the Jaw (ONJ) – A rare but serious condition causing jaw pain and delayed healing.
Atypical Bone Fractures – Unusual thigh bone fractures may occur.
Serious Infections – Increased risk of skin, urinary tract, or lung infections.
Severe Allergic Reactions – Swelling of the face, difficulty breathing, dizziness.
Seek immediate medical attention if any severe side effects occur.
60 mg every 6 months as a subcutaneous injection.
60 mg every 6 months to reduce the risk of fractures in patients undergoing hormone therapy.
Important:
Calcium and Vitamin D supplements are recommended during treatment.
Regular blood tests are required to monitor calcium levels.
Given subcutaneously (SC) in the upper arm, thigh, or abdomen.
Administered by a healthcare professional (self-administration is not recommended).
Before use, allow the injection to reach room temperature for 30 minutes.
Do not shake or dilute the solution.
Monitor calcium levels regularly to prevent hypocalcemia.
Dental check-ups are recommended to prevent jaw osteonecrosis.
Avoid invasive dental procedures while on treatment.
Not recommended in pregnancy or breastfeeding.
Patients with kidney disease require close monitoring due to increased risk of hypocalcemia.
Prolia 60mg may interact with:
Calcium & Vitamin D Supplements – Essential to reduce hypocalcemia risk.
Corticosteroids (Prednisone, Dexamethasone) – May worsen bone loss.
Chemotherapy & Immunosuppressants – Increases infection risk.
Bisphosphonates (Zoledronic Acid, Alendronate) – Avoid using together.
Live Vaccines – May reduce immune response.
Inform your doctor about all medications you are taking.
Do not use if allergic to Denosumab or any inactive ingredients.
Symptoms of an allergic reaction: rash, swelling, difficulty breathing, dizziness.
Seek emergency medical help if severe allergic reactions occur.
Severe low calcium levels (muscle spasms, confusion, seizures, irregular heartbeat)
Bone pain or unusual fractures
Severe fatigue or weakness
Seek immediate medical attention.
Treatment includes IV calcium supplementation and electrolyte monitoring.
If a dose is missed, take it as soon as possible.
Do not double the dose to compensate for a missed one.
Long delays in dosing may increase the risk of fractures.
Ensure adequate intake of calcium and vitamin D.
Regular dental check-ups are required to monitor for jaw problems.
Monitor kidney function if at risk of hypocalcemia.
Patients undergoing chemotherapy or radiation should consult their doctor before use.