Product Introduction:
Abtmed 250 mg is used in the treatment of metastatic prostate cancer, a condition where cancer has spread beyond the prostate gland. Prostate cancer cells rely on testosterone to grow, and this medication works by blocking testosterone production, thereby stopping or slowing tumor progression.
It is always given in combination with prednisone to manage side effects such as fluid retention and high blood pressure.
Uses of Abtmed 250 mg
Abtmed is primarily prescribed for:
-
Metastatic Castration-Resistant Prostate Cancer (mCRPC) – When prostate cancer continues to spread despite previous hormone therapy or surgical castration.
-
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) – Helps in the early stages of advanced prostate cancer to slow its progression.
-
Delaying Chemotherapy – Used to postpone chemotherapy in men with advanced prostate cancer.
-
Post-Surgical Therapy – Reduces the risk of recurrence after prostate surgery.
-
Prostate Cancer Symptom Control – Helps manage pain and urinary symptoms caused by tumor growth.
How Abtmed 250 mg Works (Mechanism of Action):
Abtmed (Abiraterone Acetate) is a CYP17 enzyme inhibitor that works by blocking testosterone production, which fuels prostate cancer growth.
-
Inhibits the CYP17 enzyme, essential for testosterone synthesis.
-
Reduces androgen production in the testes, adrenal glands, and prostate tumor cells.
-
Slows down tumor growth by cutting off its hormonal fuel supply.
-
Used with prednisone to counteract side effects like high blood pressure and fluid retention.
Dosage of Abtmed 250 mg
Recommended Dosage:
-
Standard Dose: 1000 mg per day (Four 250 mg tablets taken once daily)
-
Prednisone Required: 5 mg twice daily
-
Dose Adjustments: May be required for patients with liver problems.
Dosage for Liver Issues:
-
Patients with moderate liver impairment may need a lower dose.
-
Frequent liver function tests are required to monitor for toxicity.
Method of Administration (How to Take It)
-
Take Abtmed on an empty stomach – at least 1 hour before or 2 hours after a meal.
-
Swallow tablets whole with water.
-
Do not chew, crush, or break the tablets.
-
Take the medication at the same time daily for best results.
-
Prednisone must be taken alongside Abtmed to reduce side effects.
Side Effects of Abtmed 250 mg
Common Side Effects:
-
Fatigue & Weakness
-
High blood pressure (Hypertension)
-
Fluid retention (Swelling in legs/feet)
-
Low potassium levels (Hypokalemia)
-
Hot flashes & excessive sweating
-
Liver enzyme abnormalities
-
Joint pain (Arthralgia)
Severe Side Effects:
-
Heart problems (Irregular heartbeat, Chest pain, Heart failure)
-
Liver damage (Jaundice, Hepatitis, Elevated liver enzymes)
-
Adrenal insufficiency (Weakness, Low blood pressure, Salt imbalance)
-
Severe allergic reactions (Rash, Itching, Swelling, Breathing difficulties)
⚠️ Seek immediate medical help if you experience chest pain, severe dizziness, or yellowing of the skin.
Precautions Before Taking Abtmed 250 mg
-
Not for use in women or children – May cause severe harm if taken by pregnant women.
-
Regular blood tests required – Liver function, blood pressure, and potassium levels must be monitored.
-
Heart disease patients should use caution – Risk of cardiovascular complications.
-
Avoid grapefruit and grapefruit juice – It may increase side effects.
-
Use effective birth control – Male patients should take precautions to prevent pregnancy in their partners.
Drug Interactions (Medications That May Interact)
Abtmed 250 mg can interact with several medications, including:
Avoid using with:
-
Strong CYP3A4 inducers (e.g., Rifampin, Carbamazepine) – May reduce the effectiveness of Abtmed.
-
CYP2D6 substrates (e.g., Metoprolol, Codeine) – Can alter drug levels.
-
Blood thinners (Warfarin, Heparin) – May increase the risk of bleeding.
-
Corticosteroids (other than prednisone) – Can interfere with hormone levels.
-
Heart medications (Digoxin, Amiodarone) – Risk of heart-related side effects.
Allergy Warnings
-
Do not use if allergic to Abiraterone Acetate or any ingredient in Abtmed.
-
Signs of allergy: Rash, swelling, itching, difficulty breathing.
-
Seek emergency medical help if allergic reactions occur.
Storage Instructions
-
Store at room temperature (15-30°C or 59-86°F).
-
Keep in a dry place, away from moisture and direct sunlight.
-
Keep out of reach of children.
-
Do not use expired medication.
Overdose Information
Symptoms of overdose:
-
Severe dizziness or fainting
-
Irregular heartbeat
-
Breathing difficulty or confusion
What to do in case of overdose?
-
Seek emergency medical help immediately.
-
Visit the nearest hospital or call a poison control center.
Missed Dose Instructions
-
If you miss a dose, take it as soon as you remember.
-
If it's almost time for the next dose, skip the missed dose—do not take a double dose.
-
Never take extra tablets to compensate for a missed dose.
Additional Notes:
-
Regular medical check-ups are necessary to monitor liver function, potassium levels, and blood pressure.
-
Do not stop taking Abtmed suddenly without consulting your doctor.
-
A balanced diet, healthy lifestyle, and exercise may improve treatment outcomes.
Product Introduction:
Abtmed 250 mg is used in the treatment of metastatic prostate cancer, a condition where cancer has spread beyond the prostate gland. Prostate cancer cells rely on testosterone to grow, and this medication works by blocking testosterone production, thereby stopping or slowing tumor progression.
It is always given in combination with prednisone to manage side effects such as fluid retention and high blood pressure.
Uses of Abtmed 250 mg
Abtmed is primarily prescribed for:
-
Metastatic Castration-Resistant Prostate Cancer (mCRPC) – When prostate cancer continues to spread despite previous hormone therapy or surgical castration.
-
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) – Helps in the early stages of advanced prostate cancer to slow its progression.
-
Delaying Chemotherapy – Used to postpone chemotherapy in men with advanced prostate cancer.
-
Post-Surgical Therapy – Reduces the risk of recurrence after prostate surgery.
-
Prostate Cancer Symptom Control – Helps manage pain and urinary symptoms caused by tumor growth.
How Abtmed 250 mg Works (Mechanism of Action):
Abtmed (Abiraterone Acetate) is a CYP17 enzyme inhibitor that works by blocking testosterone production, which fuels prostate cancer growth.
-
Inhibits the CYP17 enzyme, essential for testosterone synthesis.
-
Reduces androgen production in the testes, adrenal glands, and prostate tumor cells.
-
Slows down tumor growth by cutting off its hormonal fuel supply.
-
Used with prednisone to counteract side effects like high blood pressure and fluid retention.
Dosage of Abtmed 250 mg
Recommended Dosage:
-
Standard Dose: 1000 mg per day (Four 250 mg tablets taken once daily)
-
Prednisone Required: 5 mg twice daily
-
Dose Adjustments: May be required for patients with liver problems.
Dosage for Liver Issues:
-
Patients with moderate liver impairment may need a lower dose.
-
Frequent liver function tests are required to monitor for toxicity.
Method of Administration (How to Take It)
-
Take Abtmed on an empty stomach – at least 1 hour before or 2 hours after a meal.
-
Swallow tablets whole with water.
-
Do not chew, crush, or break the tablets.
-
Take the medication at the same time daily for best results.
-
Prednisone must be taken alongside Abtmed to reduce side effects.
Side Effects of Abtmed 250 mg
Common Side Effects:
-
Fatigue & Weakness
-
High blood pressure (Hypertension)
-
Fluid retention (Swelling in legs/feet)
-
Low potassium levels (Hypokalemia)
-
Hot flashes & excessive sweating
-
Liver enzyme abnormalities
-
Joint pain (Arthralgia)
Severe Side Effects:
-
Heart problems (Irregular heartbeat, Chest pain, Heart failure)
-
Liver damage (Jaundice, Hepatitis, Elevated liver enzymes)
-
Adrenal insufficiency (Weakness, Low blood pressure, Salt imbalance)
-
Severe allergic reactions (Rash, Itching, Swelling, Breathing difficulties)
⚠️ Seek immediate medical help if you experience chest pain, severe dizziness, or yellowing of the skin.
Precautions Before Taking Abtmed 250 mg
-
Not for use in women or children – May cause severe harm if taken by pregnant women.
-
Regular blood tests required – Liver function, blood pressure, and potassium levels must be monitored.
-
Heart disease patients should use caution – Risk of cardiovascular complications.
-
Avoid grapefruit and grapefruit juice – It may increase side effects.
-
Use effective birth control – Male patients should take precautions to prevent pregnancy in their partners.
Drug Interactions (Medications That May Interact)
Abtmed 250 mg can interact with several medications, including:
Avoid using with:
-
Strong CYP3A4 inducers (e.g., Rifampin, Carbamazepine) – May reduce the effectiveness of Abtmed.
-
CYP2D6 substrates (e.g., Metoprolol, Codeine) – Can alter drug levels.
-
Blood thinners (Warfarin, Heparin) – May increase the risk of bleeding.
-
Corticosteroids (other than prednisone) – Can interfere with hormone levels.
-
Heart medications (Digoxin, Amiodarone) – Risk of heart-related side effects.
Allergy Warnings
-
Do not use if allergic to Abiraterone Acetate or any ingredient in Abtmed.
-
Signs of allergy: Rash, swelling, itching, difficulty breathing.
-
Seek emergency medical help if allergic reactions occur.
Storage Instructions
-
Store at room temperature (15-30°C or 59-86°F).
-
Keep in a dry place, away from moisture and direct sunlight.
-
Keep out of reach of children.
-
Do not use expired medication.
Overdose Information
Symptoms of overdose:
-
Severe dizziness or fainting
-
Irregular heartbeat
-
Breathing difficulty or confusion
What to do in case of overdose?
-
Seek emergency medical help immediately.
-
Visit the nearest hospital or call a poison control center.
Missed Dose Instructions
-
If you miss a dose, take it as soon as you remember.
-
If it's almost time for the next dose, skip the missed dose—do not take a double dose.
-
Never take extra tablets to compensate for a missed dose.
Additional Notes:
-
Regular medical check-ups are necessary to monitor liver function, potassium levels, and blood pressure.
-
Do not stop taking Abtmed suddenly without consulting your doctor.
-
A balanced diet, healthy lifestyle, and exercise may improve treatment outcomes.
