Product Introduction:
Purplz 100mg Injection is an alkylating agent that is commonly used to treat blood cancers. It is administered intravenously (IV) under medical supervision and works by inhibiting DNA replication in cancer cells, leading to cell death. It is especially effective in cases where other treatments have failed.
Uses of Purplz 100mg
Purplz is used in the treatment of:
-
Chronic Lymphocytic Leukemia (CLL) – A type of blood cancer affecting white blood cells.
-
Non-Hodgkin’s Lymphoma (NHL) – A type of lymphatic system cancer.
-
Multiple Myeloma (MM) – A cancer of plasma cells in the bone marrow.
-
Hodgkin’s Lymphoma (HL) (off-label use) – Used in refractory cases.
-
Other Hematologic Malignancies – Can be part of combination chemotherapy regimens.
How Purplz 100mg Works (Mechanism of Action):
-
Bendamustine is an alkylating agent that binds to DNA, causing cross-linking of DNA strands.
-
This prevents DNA replication and repair, leading to cancer cell death.
-
It also has antimetabolite properties, which interfere with cancer cell metabolism, making it more effective.
Dosage of Purplz 100mg
Typical Recommended Dose:
-
For CLL: 100 mg/m² IV on days 1 and 2 of a 28-day cycle, repeated every 4 weeks.
-
For NHL: 120 mg/m² IV on days 1 and 2 of a 21-day cycle, repeated every 3 weeks.
📌 Dosage may vary based on the patient’s health, blood counts, and doctor’s recommendation.
Method of Administration (How to Take It)
-
Administered as an intravenous (IV) infusion over 30-60 minutes.
-
Must be given by a healthcare professional in a hospital or clinic.
-
Hydration before and after infusion is recommended to prevent toxicity.
-
Anti-nausea medication may be given before administration.
Side Effects of Purplz 100mg
Common Side Effects:
-
Fatigue and weakness
-
Nausea and vomiting
-
Fever and chills
-
Low blood cell counts (anemia, neutropenia, thrombocytopenia)
-
Loss of appetite
-
Constipation or diarrhea
Severe Side Effects (Seek Medical Help Immediately):
-
Severe bone marrow suppression – Increased risk of infections and bleeding.
-
Liver toxicity – Yellowing of the skin/eyes, dark urine.
-
Kidney problems – Reduced urine output, swelling in legs.
-
Severe allergic reactions – Rash, difficulty breathing, swelling of the face.
-
Heart issues – Irregular heartbeat, chest pain.
⚠️ Regular blood tests are required to monitor side effects.
Precautions Before Taking Purplz 100mg
-
Bone Marrow Suppression: May cause dangerously low blood cell counts.
-
Infections: Patients should be monitored for fever and infections.
-
Liver & Kidney Function: Regular blood tests are required.
-
Pregnancy & Breastfeeding: Not recommended—can cause birth defects.
-
Bleeding Disorders: Avoid if you have a history of active bleeding issues.
Drug Interactions (Medications That May Interact)
Purplz may interact with:
-
Live vaccines – Avoid live vaccines while on treatment.
-
Immunosuppressants (e.g., Cyclosporine, Tacrolimus) – May increase infection risk.
-
Blood thinners (Warfarin, Aspirin) – Increases the risk of bleeding.
-
Nephrotoxic drugs (Cisplatin, Amphotericin B) – May worsen kidney function.
-
CYP1A2 inhibitors (Fluvoxamine, Ciprofloxacin) – May alter Bendamustine metabolism.
⚠️ Always inform your doctor about any medications you are taking.
Allergy Warnings
-
Do not take Purplz if allergic to Bendamustine or its ingredients.
-
Signs of an allergic reaction:
-
Swelling of face, lips, or throat
-
Difficulty breathing
-
Severe rash or itching
-
Dizziness or fainting
🚨 Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
-
Store at 2°C - 8°C (Refrigerated).
-
Do not freeze.
-
Keep the vial away from direct sunlight.
-
Use the reconstituted solution within the recommended time.
Overdose Information
Symptoms of overdose:
-
Severe nausea and vomiting
-
Profound bone marrow suppression (high risk of infections and bleeding)
-
Kidney and liver failure
What to do in case of overdose?
-
Seek immediate medical attention.
-
Hospitalization and supportive care may be required.
Missed Dose Instructions
-
If a dose is missed, consult your doctor immediately.
-
Do not double the dose to make up for a missed infusion.
-
Follow the prescribed treatment schedule strictly.
Product Introduction:
Purplz 100mg Injection is an alkylating agent that is commonly used to treat blood cancers. It is administered intravenously (IV) under medical supervision and works by inhibiting DNA replication in cancer cells, leading to cell death. It is especially effective in cases where other treatments have failed.
Uses of Purplz 100mg
Purplz is used in the treatment of:
-
Chronic Lymphocytic Leukemia (CLL) – A type of blood cancer affecting white blood cells.
-
Non-Hodgkin’s Lymphoma (NHL) – A type of lymphatic system cancer.
-
Multiple Myeloma (MM) – A cancer of plasma cells in the bone marrow.
-
Hodgkin’s Lymphoma (HL) (off-label use) – Used in refractory cases.
-
Other Hematologic Malignancies – Can be part of combination chemotherapy regimens.
How Purplz 100mg Works (Mechanism of Action):
-
Bendamustine is an alkylating agent that binds to DNA, causing cross-linking of DNA strands.
-
This prevents DNA replication and repair, leading to cancer cell death.
-
It also has antimetabolite properties, which interfere with cancer cell metabolism, making it more effective.
Dosage of Purplz 100mg
Typical Recommended Dose:
-
For CLL: 100 mg/m² IV on days 1 and 2 of a 28-day cycle, repeated every 4 weeks.
-
For NHL: 120 mg/m² IV on days 1 and 2 of a 21-day cycle, repeated every 3 weeks.
📌 Dosage may vary based on the patient’s health, blood counts, and doctor’s recommendation.
Method of Administration (How to Take It)
-
Administered as an intravenous (IV) infusion over 30-60 minutes.
-
Must be given by a healthcare professional in a hospital or clinic.
-
Hydration before and after infusion is recommended to prevent toxicity.
-
Anti-nausea medication may be given before administration.
Side Effects of Purplz 100mg
Common Side Effects:
-
Fatigue and weakness
-
Nausea and vomiting
-
Fever and chills
-
Low blood cell counts (anemia, neutropenia, thrombocytopenia)
-
Loss of appetite
-
Constipation or diarrhea
Severe Side Effects (Seek Medical Help Immediately):
-
Severe bone marrow suppression – Increased risk of infections and bleeding.
-
Liver toxicity – Yellowing of the skin/eyes, dark urine.
-
Kidney problems – Reduced urine output, swelling in legs.
-
Severe allergic reactions – Rash, difficulty breathing, swelling of the face.
-
Heart issues – Irregular heartbeat, chest pain.
⚠️ Regular blood tests are required to monitor side effects.
Precautions Before Taking Purplz 100mg
-
Bone Marrow Suppression: May cause dangerously low blood cell counts.
-
Infections: Patients should be monitored for fever and infections.
-
Liver & Kidney Function: Regular blood tests are required.
-
Pregnancy & Breastfeeding: Not recommended—can cause birth defects.
-
Bleeding Disorders: Avoid if you have a history of active bleeding issues.
Drug Interactions (Medications That May Interact)
Purplz may interact with:
-
Live vaccines – Avoid live vaccines while on treatment.
-
Immunosuppressants (e.g., Cyclosporine, Tacrolimus) – May increase infection risk.
-
Blood thinners (Warfarin, Aspirin) – Increases the risk of bleeding.
-
Nephrotoxic drugs (Cisplatin, Amphotericin B) – May worsen kidney function.
-
CYP1A2 inhibitors (Fluvoxamine, Ciprofloxacin) – May alter Bendamustine metabolism.
⚠️ Always inform your doctor about any medications you are taking.
Allergy Warnings
-
Do not take Purplz if allergic to Bendamustine or its ingredients.
-
Signs of an allergic reaction:
-
Swelling of face, lips, or throat
-
Difficulty breathing
-
Severe rash or itching
-
Dizziness or fainting
🚨 Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
-
Store at 2°C - 8°C (Refrigerated).
-
Do not freeze.
-
Keep the vial away from direct sunlight.
-
Use the reconstituted solution within the recommended time.
Overdose Information
Symptoms of overdose:
-
Severe nausea and vomiting
-
Profound bone marrow suppression (high risk of infections and bleeding)
-
Kidney and liver failure
What to do in case of overdose?
-
Seek immediate medical attention.
-
Hospitalization and supportive care may be required.
Missed Dose Instructions
-
If a dose is missed, consult your doctor immediately.
-
Do not double the dose to make up for a missed infusion.
-
Follow the prescribed treatment schedule strictly.
