Product Introduction:
Zecyte 500 mg is a hormonal therapy drug specifically designed for treating advanced prostate cancer, particularly in cases where the disease has spread beyond the prostate gland.
It is used in:
-
Metastatic castration-resistant prostate cancer (mCRPC) – When cancer continues to grow despite hormonal therapy.
-
Metastatic hormone-sensitive prostate cancer (mHSPC) – Used to improve survival rates in newly diagnosed advanced cases.
Since prostate cancer cells depend on male hormones (androgens) to grow, Zecyte works by blocking androgen production, helping slow cancer progression. Prednisone is always prescribed alongside Zecyte to balance hormone levels and minimize side effects.
Uses of Zecyte 500 mg
Zecyte is primarily used to treat advanced prostate cancer. The key uses include:
-
Metastatic Castration-Resistant Prostate Cancer (mCRPC) – When standard hormonal therapy no longer works.
-
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) – Helps improve survival rates when used early in the disease.
-
Delaying the Need for Chemotherapy – Helps patients avoid or postpone chemotherapy.
-
Post-Surgical Treatment – Used in some cases to prevent cancer recurrence after surgery.
-
Prostate Cancer Symptom Management – Reduces pain and discomfort caused by tumor growth.
How Zecyte 500 mg Works (Mechanism of Action):
Zecyte (Abiraterone Acetate) is a CYP17 enzyme inhibitor that blocks androgen (male hormone) production, which is essential for prostate cancer cell growth.
-
Inhibits the CYP17 enzyme, which is crucial for testosterone synthesis.
-
Prevents the adrenal glands, testes, and tumor cells from producing testosterone.
-
Lowers overall androgen levels, which helps slow down cancer progression and reduce tumor size.
Because Abiraterone disrupts hormone levels, prednisone is always given alongside Zecyte to balance hormone effects and reduce complications like high blood pressure and fluid retention.
Dosage of Zecyte 500 mg
Recommended Dosage:
-
Standard Dose: 1000 mg per day (500 mg two tablets once daily)
-
Taken with prednisone: 5 mg twice daily
-
Doctor may adjust the dose based on patient response and side effects.
Dosage Adjustments for Liver Issues:
-
Patients with liver impairment may need a lower dose.
-
Regular liver function tests are necessary during treatment.
Method of Administration (How to Take It)
-
Take Zecyte on an empty stomach, at least 1 hour before or 2 hours after a meal.
-
Swallow the tablets whole with a full glass of water.
-
Do not chew, crush, or break the tablets before swallowing.
-
Take the medication at the same time every day for best results.
-
Prednisone is required alongside Zecyte to prevent hormonal side effects.
Side Effects of Zecyte 500 mg
Common Side Effects:
-
Fatigue & Weakness
-
High blood pressure (Hypertension)
-
Swelling in legs or feet (Fluid retention/Edema)
-
Low potassium levels (Hypokalemia)
-
Hot flashes
-
Increased liver enzymes
-
Joint pain (Arthralgia)
Severe Side Effects:
-
Heart problems (Arrhythmias, Heart failure, Chest pain)
-
Severe liver damage (Hepatotoxicity, Jaundice)
-
Adrenal insufficiency (Hormonal imbalance leading to weakness, dizziness)
-
Severe allergic reactions (Rash, swelling, breathing difficulty)
⚠️ Seek immediate medical attention if you experience chest pain, severe dizziness, yellowing of the skin (jaundice), or difficulty breathing.
Precautions Before Taking Zecyte 500 mg
-
Not for use in women or children – Can cause severe harm if taken by pregnant women.
-
Regular blood tests are required to monitor potassium levels, liver function, and blood pressure.
-
Patients with heart conditions should use caution – Risk of heart complications.
-
Avoid grapefruit or grapefruit juice – Can increase drug side effects.
-
Use effective contraception – Can be harmful if a male patient’s partner is pregnant.
Drug Interactions (Medications That May Interact)
Zecyte 500 mg can interact with several medications, including:
Avoid using with:
-
Strong CYP3A4 inducers (e.g., Rifampin, Carbamazepine) – May reduce effectiveness.
-
CYP2D6 substrates (e.g., Metoprolol, Codeine) – Can alter drug levels.
-
Blood thinners (Warfarin, Heparin) – May increase bleeding risk.
-
Corticosteroids (other than prednisone) – Can cause hormonal imbalances.
-
Heart medications (Digoxin, Amiodarone) – Risk of cardiac complications.
Allergy Warnings
-
Do not use if allergic to Abiraterone Acetate or any ingredients in Zecyte.
-
Signs of allergy: Rash, swelling, severe itching, difficulty breathing.
-
Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
-
Store at room temperature (15-30°C or 59-86°F).
-
Keep in a dry place, away from moisture and direct sunlight.
-
Keep out of reach of children.
-
Do not use expired medication.
Overdose Information
Symptoms of overdose:
-
Severe dizziness or fainting
-
Irregular heartbeat
-
Confusion or trouble breathing
What to do in case of overdose?
-
Seek emergency medical help immediately.
-
Contact a poison control center or visit the nearest hospital.
Missed Dose Instructions
-
If you miss a dose, take it as soon as you remember.
-
If it is almost time for the next dose, skip the missed dose—do not take a double dose.
-
Never take extra tablets to make up for a missed dose.
Additional Notes:
-
Regular monitoring is required to check for liver function, blood pressure, and potassium levels.
-
Do not stop taking the medication suddenly without consulting a doctor.
-
A healthy diet and exercise can support better treatment outcomes.
Product Introduction:
Zecyte 500 mg is a hormonal therapy drug specifically designed for treating advanced prostate cancer, particularly in cases where the disease has spread beyond the prostate gland.
It is used in:
-
Metastatic castration-resistant prostate cancer (mCRPC) – When cancer continues to grow despite hormonal therapy.
-
Metastatic hormone-sensitive prostate cancer (mHSPC) – Used to improve survival rates in newly diagnosed advanced cases.
Since prostate cancer cells depend on male hormones (androgens) to grow, Zecyte works by blocking androgen production, helping slow cancer progression. Prednisone is always prescribed alongside Zecyte to balance hormone levels and minimize side effects.
Uses of Zecyte 500 mg
Zecyte is primarily used to treat advanced prostate cancer. The key uses include:
-
Metastatic Castration-Resistant Prostate Cancer (mCRPC) – When standard hormonal therapy no longer works.
-
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) – Helps improve survival rates when used early in the disease.
-
Delaying the Need for Chemotherapy – Helps patients avoid or postpone chemotherapy.
-
Post-Surgical Treatment – Used in some cases to prevent cancer recurrence after surgery.
-
Prostate Cancer Symptom Management – Reduces pain and discomfort caused by tumor growth.
How Zecyte 500 mg Works (Mechanism of Action):
Zecyte (Abiraterone Acetate) is a CYP17 enzyme inhibitor that blocks androgen (male hormone) production, which is essential for prostate cancer cell growth.
-
Inhibits the CYP17 enzyme, which is crucial for testosterone synthesis.
-
Prevents the adrenal glands, testes, and tumor cells from producing testosterone.
-
Lowers overall androgen levels, which helps slow down cancer progression and reduce tumor size.
Because Abiraterone disrupts hormone levels, prednisone is always given alongside Zecyte to balance hormone effects and reduce complications like high blood pressure and fluid retention.
Dosage of Zecyte 500 mg
Recommended Dosage:
-
Standard Dose: 1000 mg per day (500 mg two tablets once daily)
-
Taken with prednisone: 5 mg twice daily
-
Doctor may adjust the dose based on patient response and side effects.
Dosage Adjustments for Liver Issues:
-
Patients with liver impairment may need a lower dose.
-
Regular liver function tests are necessary during treatment.
Method of Administration (How to Take It)
-
Take Zecyte on an empty stomach, at least 1 hour before or 2 hours after a meal.
-
Swallow the tablets whole with a full glass of water.
-
Do not chew, crush, or break the tablets before swallowing.
-
Take the medication at the same time every day for best results.
-
Prednisone is required alongside Zecyte to prevent hormonal side effects.
Side Effects of Zecyte 500 mg
Common Side Effects:
-
Fatigue & Weakness
-
High blood pressure (Hypertension)
-
Swelling in legs or feet (Fluid retention/Edema)
-
Low potassium levels (Hypokalemia)
-
Hot flashes
-
Increased liver enzymes
-
Joint pain (Arthralgia)
Severe Side Effects:
-
Heart problems (Arrhythmias, Heart failure, Chest pain)
-
Severe liver damage (Hepatotoxicity, Jaundice)
-
Adrenal insufficiency (Hormonal imbalance leading to weakness, dizziness)
-
Severe allergic reactions (Rash, swelling, breathing difficulty)
⚠️ Seek immediate medical attention if you experience chest pain, severe dizziness, yellowing of the skin (jaundice), or difficulty breathing.
Precautions Before Taking Zecyte 500 mg
-
Not for use in women or children – Can cause severe harm if taken by pregnant women.
-
Regular blood tests are required to monitor potassium levels, liver function, and blood pressure.
-
Patients with heart conditions should use caution – Risk of heart complications.
-
Avoid grapefruit or grapefruit juice – Can increase drug side effects.
-
Use effective contraception – Can be harmful if a male patient’s partner is pregnant.
Drug Interactions (Medications That May Interact)
Zecyte 500 mg can interact with several medications, including:
Avoid using with:
-
Strong CYP3A4 inducers (e.g., Rifampin, Carbamazepine) – May reduce effectiveness.
-
CYP2D6 substrates (e.g., Metoprolol, Codeine) – Can alter drug levels.
-
Blood thinners (Warfarin, Heparin) – May increase bleeding risk.
-
Corticosteroids (other than prednisone) – Can cause hormonal imbalances.
-
Heart medications (Digoxin, Amiodarone) – Risk of cardiac complications.
Allergy Warnings
-
Do not use if allergic to Abiraterone Acetate or any ingredients in Zecyte.
-
Signs of allergy: Rash, swelling, severe itching, difficulty breathing.
-
Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
-
Store at room temperature (15-30°C or 59-86°F).
-
Keep in a dry place, away from moisture and direct sunlight.
-
Keep out of reach of children.
-
Do not use expired medication.
Overdose Information
Symptoms of overdose:
-
Severe dizziness or fainting
-
Irregular heartbeat
-
Confusion or trouble breathing
What to do in case of overdose?
-
Seek emergency medical help immediately.
-
Contact a poison control center or visit the nearest hospital.
Missed Dose Instructions
-
If you miss a dose, take it as soon as you remember.
-
If it is almost time for the next dose, skip the missed dose—do not take a double dose.
-
Never take extra tablets to make up for a missed dose.
Additional Notes:
-
Regular monitoring is required to check for liver function, blood pressure, and potassium levels.
-
Do not stop taking the medication suddenly without consulting a doctor.
-
A healthy diet and exercise can support better treatment outcomes.
