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Abevmy 100mg - Bevacizumab Injections

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  • Abevmy 100mg - Bevacizumab Injections

Abevmy 100mg - Bevacizumab Injections

Abevmy 100mg Injection contains Bevacizumab, a monoclonal antibody used to treat various cancers, including colorectal, lung, kidney, ovarian, and brain cancers. It works by blocking VEGF (vascular endothelial growth factor), preventing blood vessel formation in tumors, thereby slowing cancer growth.

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Description Product Details
General Information:
Generic Name: Bevacizumab
Brand Name: Abevmy
Packing: Vial
Strength: 100mg/4mL
Company: Mylan Pharmaceuticals Pvt. Ltd.
Form: Injection (Intravenous Infusion)
Category: Anti-Cancer, Monoclonal Antibody
Product Introduction:
Abevmy 100mg Injection is an anti-cancer (anti-angiogenic) medication used in chemotherapy regimens for various cancers. It is a monoclonal antibody that prevents tumor blood vessel formation, starving the tumor of oxygen and nutrients necessary for growth.
Uses of Abevmy 100mg
Abevmy 100mg is used in combination with chemotherapy for treating:
  1. Metastatic Colorectal Cancer – Used with fluoropyrimidine-based chemotherapy.
  2. Non-Small Cell Lung Cancer (NSCLC) – Combined with platinum-based chemotherapy.
  3. Metastatic Kidney Cancer (Renal Cell Carcinoma) – Often used with interferon alfa.
  4. Ovarian & Cervical Cancer – Helps slow tumor progression.
  5. Glioblastoma (Brain Cancer) – Used when other treatments fail.
  6. Hepatocellular Carcinoma (Liver Cancer) – In combination with Atezolizumab.
How Abevmy 100mg Works (Mechanism of Action):
  1. Bevacizumab targets VEGF (Vascular Endothelial Growth Factor).
  2. VEGF is responsible for forming new blood vessels in tumors (angiogenesis).
  3. By blocking VEGF, Abevmy prevents the tumor from receiving blood, oxygen, and nutrients, leading to slowed tumor growth and shrinkage.
Dosage of Abevmy 100mg
Typical Recommended Dose:
  1. Colorectal Cancer: 5 mg/kg or 10 mg/kg every 2 weeks (IV infusion)
  2. Lung Cancer (NSCLC): 15 mg/kg every 3 weeks
  3. Kidney Cancer: 10 mg/kg every 2 weeks
  4. Ovarian/Cervical Cancer: 15 mg/kg every 3 weeks
  5. Brain Cancer (Glioblastoma): 10 mg/kg every 2 weeks
⚠️ Dosage varies based on cancer type, body weight, and chemotherapy regimen. Always follow your oncologist’s prescription.
Method of Administration (How to Take It)
  1. Administered as an intravenous (IV) infusion over 30-90 minutes.
  2. First dose is given slowly (90 min) to check for reactions.
  3. Subsequent infusions may be faster if tolerated.
  4. Should only be given by a healthcare professional.
Side Effects of Abevmy 100mg
Common Side Effects:
  1. High blood pressure (Hypertension)
  2. Fatigue & Weakness
  3. Bleeding (Nosebleeds, Gum Bleeding)
  4. Delayed wound healing
  5. Mouth sores & loss of appetite
Severe Side Effects (Seek Immediate Medical Help):
  1. Severe bleeding (coughing blood, gastrointestinal bleeding)
  2. Perforations in the stomach/intestines (severe abdominal pain)
  3. Blood clots leading to stroke or heart attack
  4. Kidney problems (Protein in urine, Swelling in legs)
  5. Severe allergic reactions (Swelling, difficulty breathing, rash)
🚨 If serious side effects occur, seek emergency medical attention.
Precautions Before Taking Abevmy 100mg
  1. High Blood Pressure: Patients with hypertension should be closely monitored.
  2. Surgery: Avoid use 4 weeks before and after surgery due to delayed wound healing.
  3. Bleeding Disorders: Bevacizumab increases bleeding risk.
  4. Pregnancy & Breastfeeding: Not safe – Can cause fetal harm.
  5. Kidney Disease: Monitor protein levels in urine.
Drug Interactions (Medications That May Interact)
Abevmy 100mg may interact with:
  1. Warfarin & Blood Thinners: Increases bleeding risk.
  2. NSAIDs (Ibuprofen, Aspirin): May worsen bleeding side effects.
  3. Platinum-Based Chemotherapy (Cisplatin, Carboplatin): Increases kidney toxicity.
  4. Anti-Hypertensive Medications: May require dose adjustment.
⚠️ Always inform your doctor about all medications you are taking.
Allergy Warnings
  1. Do not take if allergic to Bevacizumab or similar monoclonal antibodies.
  2. Symptoms of an allergic reaction:
    1. Swelling, Rash, Itching
    2. Shortness of breath, Chest tightness
    3. Severe dizziness
🚨 Seek emergency medical help if allergic symptoms occur.
Storage Instructions
  1. Store at 2°C - 8°C (Refrigerated).
  2. Do not freeze or shake the vial.
  3. Keep away from light.
  4. Use within the prescribed period after opening.
Overdose Information
Symptoms of Overdose:
  1. Severe high blood pressure
  2. Excessive bleeding
  3. Kidney damage (Severe swelling, Reduced urine output)
What to Do in Case of Overdose?
  1. Seek immediate medical attention.
  2. Blood pressure monitoring and supportive treatment required.
Missed Dose Instructions
  1. If a dose is missed, reschedule with the doctor as soon as possible.
  2. Do not double the dose to compensate.

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