Product Introduction:
Biomab EGFR 200mg Injection is an anti-cancer therapy that specifically inhibits EGFR, a protein responsible for the growth and spread of cancer cells. It is used in combination with chemotherapy and radiation therapy for better treatment outcomes in head & neck cancers and gliomas.
Uses of Biomab EGFR 200mg
Biomab EGFR 200mg is used for treating:
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Head and Neck Squamous Cell Carcinoma (HNSCC) – Used with radiation/chemotherapy.
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Glioma (Brain Tumors) – Used in both pediatric and adult patients.
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Non-Small Cell Lung Cancer (NSCLC) (Off-label Use) – In combination therapy.
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Colorectal Cancer (Off-label Use) – For patients with EGFR overexpression.
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Other EGFR-Expressing Tumors – Investigational use in other cancers.
How Biomab EGFR 200mg Works (Mechanism of Action):
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Nimotuzumab binds to EGFR, preventing it from activating tumor growth.
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EGFR plays a crucial role in cell division, survival, and tumor spread.
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Blocking EGFR slows down cancer cell growth and increases the effectiveness of chemotherapy/radiation therapy.
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Unlike other EGFR inhibitors, Biomab has fewer skin-related side effects, making it well tolerated.
Dosage of Biomab EGFR 200mg
Typical Recommended Dose:
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Head & Neck Cancer:
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Gliomas (Brain Tumors):
📌 Dosage may vary based on the patient’s condition and oncologist’s recommendation.
Method of Administration (How to Take It)
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Administered as an intravenous (IV) infusion in a hospital or clinic.
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Infusion time: Over 30 to 60 minutes.
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Not for self-administration – must be given by a healthcare professional.
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Can be used alone or in combination with chemotherapy/radiation therapy.
Side Effects of Biomab EGFR 200mg
Common Side Effects:
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Fatigue and weakness
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Fever or chills
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Nausea and vomiting
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Mild skin rash
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Headache
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Loss of appetite
Severe Side Effects (Seek Immediate Medical Help):
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Severe allergic reactions – Swelling, difficulty breathing.
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Severe infusion reactions – Drop in blood pressure, fever, chills.
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Liver toxicity – Yellowing of skin/eyes.
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Low blood cell counts – Increased risk of infections.
⚠️ Biomab has fewer skin-related side effects compared to other EGFR inhibitors.
Precautions Before Taking Biomab EGFR 200mg
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Pregnant & Breastfeeding Women: Avoid use due to unknown fetal effects.
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Liver & Kidney Disease: Requires regular monitoring.
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Patients Undergoing Radiation: Enhances radiation effects, but must be used cautiously.
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Autoimmune Disorders: May worsen conditions like lupus or rheumatoid arthritis.
Drug Interactions (Medications That May Interact)
Biomab EGFR 200mg may interact with:
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Chemotherapy Drugs (Cisplatin, 5-Fluorouracil, Paclitaxel): May increase toxicity.
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Radiotherapy: Can enhance radiation effects.
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Immunosuppressants (Steroids, Methotrexate): May reduce effectiveness.
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Live Vaccines: Avoid while on treatment.
⚠️ Inform your doctor about all medications and supplements before starting therapy.
Allergy Warnings
🚨 Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
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Store in a refrigerator at 2°C - 8°C.
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Do not freeze or shake the vial.
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Protect from light and heat.
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Use within the prescribed period after dilution.
Overdose Information
Symptoms of Overdose:
What to Do in Case of Overdose?
Missed Dose Instructions
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Contact your doctor immediately if a dose is missed.
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Do not self-administer a missed dose.
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Do not double up on doses.
