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Fulveser 250mg - Fulvestrant Injection

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Fulveser 250mg - Fulvestrant Injection

Fulveser 250mg is a prescription injection used in the treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women. It is a targeted hormone therapy that works by degrading estrogen receptors in cancer cells.

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Description Product Details
General Information:
Generic Name: Fulvestrant
Brand Name: Fulveser
Packing: Single-dose vial or prefilled syringe
Strength: 250mg/5ml
Manufacturer: Samarth Life Sciences Pvt. Ltd.
Form: Injection
Category: Hormonal Therapy / Estrogen Receptor Antagonist (SERD)
Product Intro:
Fulveser 250mg Injection is a hormonal anticancer medication indicated for advanced or metastatic breast cancer in women whose disease has progressed following previous hormone therapy. It is administered as a slow intramuscular injection by a healthcare professional.
Uses:
Fulveser is indicated for the treatment of:
  1. Hormone receptor-positive metastatic breast cancer
  2. Postmenopausal women with disease progression after anti-estrogen therapy
  3. Advanced breast cancer resistant to Tamoxifen
  4. Hormone receptor-positive, HER2-negative breast cancer
  5. In combination with CDK4/6 inhibitors like Palbociclib
  6. As a monotherapy or part of combination endocrine therapy
Storage Instructions:
  1. Store between 2°C to 8°C in a refrigerator
  2. Do not freeze
  3. Protect from direct light
  4. Keep out of reach of children
  5. Allow to reach room temperature before use
How it Works (Mechanism of Action):
Fulvestrant is a Selective Estrogen Receptor Degrader (SERD). It binds to estrogen receptors and accelerates their degradation. By eliminating these receptors, the estrogen-dependent growth of breast cancer cells is inhibited.
Side Effects:
Common Side Effects:
  1. Headache
  2. Hot flashes
  3. Nausea
  4. Fatigue
  5. Joint and muscle pain
  6. Injection site reactions (pain, swelling)
Severe Side Effects:
  1. Liver dysfunction (increased liver enzymes)
  2. Blood clot formation
  3. Vaginal bleeding
  4. Allergic reactions (rash, swelling, anaphylaxis)
Dosage (Typical Recommended Dose):
  1. Initial Dose: 500 mg on Days 1, 15, and 29
  2. Maintenance Dose: 500 mg every 28 days thereafter
  3. Given as two intramuscular injections (each 5 ml, one in each buttock)
Method of Administration:
  1. Administered intramuscularly (IM) in the gluteal muscle
  2. To be given only by a healthcare professional
  3. Ensure proper aseptic technique during administration
Precautions:
  1. Not recommended during pregnancy or breastfeeding
  2. Caution in patients with liver impairment
  3. Avoid use in premenopausal women, unless under strict supervision
  4. Inform your doctor of any bleeding disorders or liver disease
  5. Monitor liver function tests (LFTs) regularly
Drug Interactions:
  1. Minimal known drug interactions
  2. Use cautiously with anticoagulants like warfarin
  3. Always provide a full list of medications and supplements to your doctor
Allergies:
  1. Contraindicated in patients with hypersensitivity to Fulvestrant or its ingredients
  2. Signs of an allergic reaction include rash, swelling, breathing difficulties, dizziness
Overdose Information:
  1. Unlikely due to professional administration
  2. In case of overdose, provide supportive care and monitoring
  3. Seek immediate medical assistance if adverse symptoms occur
Missed Dose Instructions:
  1. Contact your healthcare provider to reschedule missed doses
  2. Do not self-administer or double the dose
  3. Continue with the regular injection cycle as prescribed
Additional Notes:
  1. Fulveser is part of advanced hormone therapy and often used in combination with other anticancer medications
  2. Periodic monitoring and imaging may be needed to assess treatment response
  3. Effective contraception is advised during and after treatment
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