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Albucel 20% - Human Normal Albumin

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Albucel 20% - Human Normal Albumin

Albucel 20% is a sterile, purified human albumin solution used for restoring and maintaining blood volume in various medical conditions like shock, burns, and hypoalbuminemia. It is a plasma volume expander commonly administered in critical care.

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Description Product Details
General Information:
Generic Name: Human Normal Albumin
Brand Name: Albucel 20%
Packing: Vial
Strength: 20% solution (20g/100mL)
Manufacturer: Intas Pharmaceuticals
Form: Injectable solution
Category: Plasma Volume Expander / Blood Product
Product Intro:
Albucel 20% contains Human Normal Albumin, a naturally occurring protein found in blood plasma. It helps maintain oncotic pressure and is crucial for the regulation of blood volume. This 20% concentrated form is often used when rapid volume expansion is needed in critically ill patients.
Uses:
Albucel 20% is used for the following indications:
  1. Hypovolemia (low blood volume)
  2. Hypoalbuminemia (low albumin levels)
  3. Burns and severe trauma
  4. Hemodialysis-related complications
  5. Acute liver failure and ascites
  6. Cardiopulmonary bypass surgery support
Storage Instructions:
  1. Store at 2°C to 25°C
  2. Do not freeze
  3. Keep in the original package to protect from light
  4. Once opened, use immediately or discard unused portion
How it Works (Mechanism of Action):
Human albumin maintains oncotic pressure by attracting fluid into the blood vessels from surrounding tissues. This helps in volume replacement and stabilizing circulatory functions, especially during shock, trauma, and surgeries.
Side Effects:
Common Side Effects:
  1. Mild fever
  2. Flushing
  3. Nausea
  4. Rash
  5. Chills
Severe Side Effects:
  1. Hypersensitivity or allergic reactions (including anaphylaxis)
  2. Pulmonary edema (fluid in lungs)
  3. Hypotension
  4. Tachycardia
  5. Electrolyte imbalance
Dosage (Typical Recommended Dose):
  1. Dosage is patient-specific, based on body weight and clinical condition
  2. For adults: Typically 100 mL of 20% solution given as a slow IV infusion
  3. Must be guided by clinical response and lab values (especially albumin and plasma volume)
Method of Administration:
  1. Intravenous infusion only
  2. Administer using appropriate sterile technique
  3. Infuse slowly; monitor for volume overload
  4. Dilution with isotonic saline may be done if required
Precautions:
  1. Use with caution in patients with heart failure, renal impairment, or severe anemia
  2. Monitor blood pressure, heart rate, and fluid balance
  3. Ensure adequate hydration before use
  4. Use caution in dehydrated patients without fluid resuscitation
  5. Do not mix with other IV drugs in the same line
Drug Interactions:
  1. No specific drug-drug interactions known, but avoid mixing with incompatible IV drugs
  2. Monitor closely when given alongside diuretics or antihypertensives
Allergies:
  1. Contraindicated in patients with known hypersensitivity to albumin preparations
  2. Watch for signs of allergic reaction such as rash, difficulty breathing, or swelling
Overdose Information:
  1. Overdose may lead to hypervolemia or pulmonary edema
  2. Immediate intervention includes stopping infusion, diuretics, and respiratory support if needed
Missed Dose Instructions:
  1. Since it's used in acute care, dosing is determined by medical professionals
  2. If a dose is delayed, consult with a healthcare provider before proceeding
Additional Notes:
  1. Sourced from human plasma; rigorous viral screening and pasteurization applied to reduce infection risks
  2. Suitable for adults and children under clinical supervision
  3. Should be used only under medical guidance in a hospital setting
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