Product Introduction:
Olimab 60mg is a prescription bone-strengthening therapy primarily used to treat osteoporosis and bone loss due to cancer treatments. It helps maintain bone density, reduces fracture risks, and enhances bone strength. By blocking RANKL, it prevents bone breakdown and maintains skeletal integrity.
Uses of Olimab 60mg Injection:
Olimab 60mg is prescribed for:
-
Osteoporosis in Postmenopausal Women – Reduces the risk of vertebral, hip, and non-vertebral fractures.
-
Osteoporosis in Men – Helps improve bone density in aging males.
-
Bone Loss Due to Cancer Treatments – Prevents bone loss in prostate and breast cancer patients receiving hormone therapy.
-
Glucocorticoid-Induced Osteoporosis – Used in patients on long-term steroid therapy that weakens bones.
-
Paget’s Disease of Bone (Off-label Use) – Helps manage abnormal bone remodeling in this condition.
Storage Instructions:
-
Store in a refrigerator (2°C – 8°C).
-
Do not freeze or expose to high temperatures.
-
Keep in original packaging to protect from light.
-
Before use, allow the injection to reach room temperature (about 30 minutes).
-
Do not shake the vial or syringe.
How Olimab 60mg Works (Mechanism of Action):
Denosumab is a RANK Ligand (RANKL) inhibitor that:
-
Prevents osteoclast activation – Inhibits the cells responsible for breaking down bone.
-
Slows bone loss and increases bone density – Maintains stronger bones by reducing bone resorption.
-
Reduces fracture risk – Helps prevent osteoporosis-related fractures in high-risk patients.
Side Effects:
Common Side Effects:
-
Low calcium levels (Hypocalcemia)
-
Back pain and joint pain
-
Fatigue and weakness
-
Skin rash or eczema
-
Flu-like symptoms
-
Mild swelling or redness at the injection site
Severe Side Effects (Rare but Serious):
-
Severe Hypocalcemia (muscle cramps, confusion, irregular heartbeat, seizures)
-
Osteonecrosis of the Jaw (ONJ) – A rare but serious condition causing jaw pain and delayed healing.
-
Atypical Bone Fractures – Unusual thigh bone fractures may occur.
-
Serious Infections – Increased risk of skin, urinary tract, or lung infections.
-
Severe Allergic Reactions – Swelling of the face, difficulty breathing, dizziness.
Seek immediate medical attention if any severe side effects occur.
Dosage (Typical Recommended Dose):
For Osteoporosis in Postmenopausal Women & Men:
-
60 mg every 6 months as a subcutaneous injection.
For Bone Loss Due to Cancer Therapy:
-
60 mg every 6 months to reduce the risk of fractures in patients undergoing hormone therapy.
Important:
-
Calcium and Vitamin D supplements are recommended during treatment.
-
Regular blood tests are required to monitor calcium levels.
Method of Administration:
-
Given subcutaneously (SC) in the upper arm, thigh, or abdomen.
-
Administered by a healthcare professional (self-administration is not recommended).
-
Before use, allow the injection to reach room temperature for 30 minutes.
-
Do not shake or dilute the solution.
Precautions:
-
Monitor calcium levels regularly to prevent hypocalcemia.
-
Dental check-ups are recommended to prevent jaw osteonecrosis.
-
Avoid invasive dental procedures while on treatment.
-
Not recommended in pregnancy or breastfeeding.
-
Patients with kidney disease require close monitoring due to increased risk of hypocalcemia.
Drug Interactions:
Olimab 60mg may interact with:
-
Calcium & Vitamin D Supplements – Essential to reduce hypocalcemia risk.
-
Corticosteroids (Prednisone, Dexamethasone) – May worsen bone loss.
-
Chemotherapy & Immunosuppressants – Increases infection risk.
-
Bisphosphonates (Zoledronic Acid, Alendronate) – Avoid using together.
-
Live Vaccines – May reduce immune response.
Inform your doctor about all medications you are taking.
Allergies (Warnings for Allergic Reactions):
-
Do not use if allergic to Denosumab or any inactive ingredients.
-
Symptoms of an allergic reaction: rash, swelling, difficulty breathing, dizziness.
-
Seek emergency medical help if severe allergic reactions occur.
Overdose Information:
Symptoms of overdose:
-
Severe low calcium levels (muscle spasms, confusion, seizures, irregular heartbeat)
-
Bone pain or unusual fractures
-
Severe fatigue or weakness
What to do in case of overdose?
-
Seek immediate medical attention.
-
Treatment includes IV calcium supplementation and electrolyte monitoring.
Missed Dose Instructions:
-
If a dose is missed, take it as soon as possible.
-
Do not double the dose to compensate for a missed one.
-
Long delays in dosing may increase the risk of fractures.
Additional Notes:
-
Ensure adequate intake of calcium and vitamin D.
-
Regular dental check-ups are required to monitor for jaw problems.
-
Monitor kidney function if at risk of hypocalcemia.
-
Patients undergoing chemotherapy or radiation should consult their doctor before use.
Product Introduction:
Olimab 60mg is a prescription bone-strengthening therapy primarily used to treat osteoporosis and bone loss due to cancer treatments. It helps maintain bone density, reduces fracture risks, and enhances bone strength. By blocking RANKL, it prevents bone breakdown and maintains skeletal integrity.
Uses of Olimab 60mg Injection:
Olimab 60mg is prescribed for:
-
Osteoporosis in Postmenopausal Women – Reduces the risk of vertebral, hip, and non-vertebral fractures.
-
Osteoporosis in Men – Helps improve bone density in aging males.
-
Bone Loss Due to Cancer Treatments – Prevents bone loss in prostate and breast cancer patients receiving hormone therapy.
-
Glucocorticoid-Induced Osteoporosis – Used in patients on long-term steroid therapy that weakens bones.
-
Paget’s Disease of Bone (Off-label Use) – Helps manage abnormal bone remodeling in this condition.
Storage Instructions:
-
Store in a refrigerator (2°C – 8°C).
-
Do not freeze or expose to high temperatures.
-
Keep in original packaging to protect from light.
-
Before use, allow the injection to reach room temperature (about 30 minutes).
-
Do not shake the vial or syringe.
How Olimab 60mg Works (Mechanism of Action):
Denosumab is a RANK Ligand (RANKL) inhibitor that:
-
Prevents osteoclast activation – Inhibits the cells responsible for breaking down bone.
-
Slows bone loss and increases bone density – Maintains stronger bones by reducing bone resorption.
-
Reduces fracture risk – Helps prevent osteoporosis-related fractures in high-risk patients.
Side Effects:
Common Side Effects:
-
Low calcium levels (Hypocalcemia)
-
Back pain and joint pain
-
Fatigue and weakness
-
Skin rash or eczema
-
Flu-like symptoms
-
Mild swelling or redness at the injection site
Severe Side Effects (Rare but Serious):
-
Severe Hypocalcemia (muscle cramps, confusion, irregular heartbeat, seizures)
-
Osteonecrosis of the Jaw (ONJ) – A rare but serious condition causing jaw pain and delayed healing.
-
Atypical Bone Fractures – Unusual thigh bone fractures may occur.
-
Serious Infections – Increased risk of skin, urinary tract, or lung infections.
-
Severe Allergic Reactions – Swelling of the face, difficulty breathing, dizziness.
Seek immediate medical attention if any severe side effects occur.
Dosage (Typical Recommended Dose):
For Osteoporosis in Postmenopausal Women & Men:
-
60 mg every 6 months as a subcutaneous injection.
For Bone Loss Due to Cancer Therapy:
-
60 mg every 6 months to reduce the risk of fractures in patients undergoing hormone therapy.
Important:
-
Calcium and Vitamin D supplements are recommended during treatment.
-
Regular blood tests are required to monitor calcium levels.
Method of Administration:
-
Given subcutaneously (SC) in the upper arm, thigh, or abdomen.
-
Administered by a healthcare professional (self-administration is not recommended).
-
Before use, allow the injection to reach room temperature for 30 minutes.
-
Do not shake or dilute the solution.
Precautions:
-
Monitor calcium levels regularly to prevent hypocalcemia.
-
Dental check-ups are recommended to prevent jaw osteonecrosis.
-
Avoid invasive dental procedures while on treatment.
-
Not recommended in pregnancy or breastfeeding.
-
Patients with kidney disease require close monitoring due to increased risk of hypocalcemia.
Drug Interactions:
Olimab 60mg may interact with:
-
Calcium & Vitamin D Supplements – Essential to reduce hypocalcemia risk.
-
Corticosteroids (Prednisone, Dexamethasone) – May worsen bone loss.
-
Chemotherapy & Immunosuppressants – Increases infection risk.
-
Bisphosphonates (Zoledronic Acid, Alendronate) – Avoid using together.
-
Live Vaccines – May reduce immune response.
Inform your doctor about all medications you are taking.
Allergies (Warnings for Allergic Reactions):
-
Do not use if allergic to Denosumab or any inactive ingredients.
-
Symptoms of an allergic reaction: rash, swelling, difficulty breathing, dizziness.
-
Seek emergency medical help if severe allergic reactions occur.
Overdose Information:
Symptoms of overdose:
-
Severe low calcium levels (muscle spasms, confusion, seizures, irregular heartbeat)
-
Bone pain or unusual fractures
-
Severe fatigue or weakness
What to do in case of overdose?
-
Seek immediate medical attention.
-
Treatment includes IV calcium supplementation and electrolyte monitoring.
Missed Dose Instructions:
-
If a dose is missed, take it as soon as possible.
-
Do not double the dose to compensate for a missed one.
-
Long delays in dosing may increase the risk of fractures.
Additional Notes:
-
Ensure adequate intake of calcium and vitamin D.
-
Regular dental check-ups are required to monitor for jaw problems.
-
Monitor kidney function if at risk of hypocalcemia.
-
Patients undergoing chemotherapy or radiation should consult their doctor before use.
