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Taceedo 80mg - Docetaxel Injection Ip Concentrate

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  • Taceedo 80mg - Docetaxel Injection Ip Concentrate

Taceedo 80mg - Docetaxel Injection Ip Concentrate

Taceedo 80mg is a Docetaxel Injection IP Concentrate used for the treatment of various cancers, including breast cancer, lung cancer, prostate cancer, gastric cancer, and head & neck cancer. It works by inhibiting cancer cell division, preventing tumor growth, and inducing programmed cell death (apoptosis).

  • ₹1500

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Description Product Details
General Information:
Generic Name: Docetaxel Injection IP
Brand Name: Taceedo
Packing: Vial
Strength: 80 mg
Manufacturer: Miracalus
Form: Intravenous Injection
Category: Chemotherapy / Antineoplastic Agent / Taxane Derivative
Product Introduction:
Taceedo 80mg is a concentrated formulation of Docetaxel, a taxane-based chemotherapy drug widely used in the treatment of solid tumors. It is administered as an intravenous (IV) infusion under the supervision of an oncologist. Taceedo 80mg works by inhibiting microtubule function, leading to cell cycle arrest and cancer cell death.
Uses of Taceedo 80mg Injection:
Taceedo 80mg is prescribed for the treatment of:
  1. Breast Cancer – Used alone or with other chemotherapy drugs in advanced or metastatic breast cancer.
  2. Non-Small Cell Lung Cancer (NSCLC) – Often used in combination with platinum-based drugs.
  3. Prostate Cancer – Treats metastatic hormone-refractory prostate cancer, usually combined with Prednisone.
  4. Gastric (Stomach) Cancer – Given as part of a combination regimen for advanced gastric cancer.
  5. Head & Neck Cancer – Used in the treatment of locally advanced or metastatic squamous cell carcinoma.
  6. Ovarian Cancer (Off-label Use) – Sometimes used in platinum-resistant ovarian cancer cases.
Storage Instructions:
  1. Store at 2°C – 8°C (refrigerated temperature).
  2. Do not freeze or expose to extreme heat.
  3. Protect from light by keeping in its original packaging.
  4. Shake well before use if required.
  5. Discard any unused portion following medical waste disposal guidelines.
How Taceedo 80mg Works (Mechanism of Action):
Docetaxel is a microtubule stabilizer that:
  1. Prevents cancer cell division – Binds to tubulin, stabilizing microtubules and inhibiting mitotic cell division.
  2. Induces apoptosis (programmed cell death) – Leads to cancer cell destruction.
  3. Inhibits angiogenesis – Reduces tumor blood supply, restricting tumor growth.
Side Effects:
Common Side Effects:
  1. Fatigue and weakness
  2. Nausea and vomiting
  3. Hair loss (alopecia)
  4. Low blood counts (neutropenia, anemia, thrombocytopenia)
  5. Loss of appetite
  6. Peripheral neuropathy (numbness or tingling)
  7. Skin rash or nail discoloration
Severe Side Effects (Rare but Serious):
  1. Severe allergic reactions – Swelling, breathing difficulty, rash
  2. Febrile neutropenia – Low white blood cells with fever, increasing infection risk
  3. Severe liver toxicity – Jaundice, elevated liver enzymes
  4. Fluid retention syndrome – Swelling in limbs, lung congestion
  5. Severe neuropathy – Permanent nerve damage
Seek immediate medical help if severe side effects occur.
Dosage (Typical Recommended Dose):
Standard Chemotherapy Dosage (Varies by Cancer Type):
  1. Breast Cancer / Lung Cancer / Stomach Cancer / Head & Neck Cancer:
    1. 75–100 mg/m² IV infusion every 3 weeks, often with pre-medications.
  2. Prostate Cancer:
    1. 75 mg/m² IV infusion every 3 weeks + Prednisone.
  3. Reduced Dosages for High-Risk Patients:
    1. 60 mg/m² IV infusion for elderly or weak patients.
The dosage is adjusted based on body surface area (BSA), blood test results, and patient response.
Method of Administration:
  1. Administered as an intravenous (IV) infusion over 1 hour.
  2. Given under the supervision of an oncologist in a hospital or clinic.
  3. Pre-medication with corticosteroids (e.g., Dexamethasone) is required to reduce allergic reactions and fluid retention.
  4. Blood tests and hydration are necessary before each chemotherapy cycle.
Precautions:
  1. Pre-medication (corticosteroids) helps reduce fluid retention and hypersensitivity reactions.
  2. Frequent blood tests are required to monitor white blood cell count and liver function.
  3. Avoid live vaccines while undergoing chemotherapy.
  4. Use effective contraception during and 6 months after treatment (for both men and women).
  5. Not recommended during pregnancy or breastfeeding.
  6. Patients with liver disease require dose adjustments and close monitoring.
Drug Interactions:
Taceedo 80mg may interact with:
  1. CYP3A4 inhibitors (Ketoconazole, Ritonavir, Clarithromycin) – Increases toxicity.
  2. CYP3A4 inducers (Rifampin, Carbamazepine, Phenytoin) – Reduces drug effectiveness.
  3. Blood Thinners (Warfarin, Aspirin) – Increases bleeding risk.
  4. Other Chemotherapy Drugs (Cisplatin, Doxorubicin, Capecitabine) – Requires careful dose adjustments.
  5. Live Vaccines – Increased risk of severe infections due to weakened immunity.
Inform your doctor about all medications you are taking.
Allergies (Warnings for Allergic Reactions):
  1. Do not use if allergic to Docetaxel or its excipients.
  2. Symptoms of an allergic reaction include rash, swelling, difficulty breathing, dizziness.
  3. Pre-medication with corticosteroids is required to prevent severe reactions.
Overdose Information:
Symptoms of Overdose:
  1. Severe neutropenia (low white blood cells)
  2. Severe nausea, vomiting, and diarrhea
  3. Organ failure (kidney/liver damage)
  4. Severe allergic reaction or breathing difficulty
What to do in case of overdose?
  1. Seek immediate medical attention.
  2. Supportive care includes IV fluids, blood transfusion, and symptom management.
Missed Dose Instructions:
  1. If a dose is missed, the doctor will reschedule the next infusion.
  2. Do not self-administer or double the dose.
  3. Maintain regular follow-ups to avoid treatment delays.
Additional Notes:
  1. Hydration is essential to prevent kidney damage.
  2. Follow a neutropenic diet to minimize infection risk.
  3. Regular liver function tests are necessary.
  4. Hair loss is temporary and usually resolves after treatment.

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