Product Introduction:
Prostiga 250 mg is a hormonal therapy drug used in metastatic prostate cancer. Prostate cancer cells depend on testosterone to grow and spread, and this medication helps reduce testosterone production, slowing the progression of the disease.
Prednisone is prescribed alongside Prostiga to prevent side effects such as high blood pressure and fluid retention.
Uses of Prostiga 250 mg
Prostiga is primarily used for treating advanced-stage prostate cancer, including:
-
Metastatic Castration-Resistant Prostate Cancer (mCRPC) – For patients whose cancer continues to grow despite previous hormonal therapy or surgical castration.
-
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) – For newly diagnosed advanced prostate cancer to slow progression.
-
Delaying Chemotherapy – Helps in postponing chemotherapy in advanced prostate cancer patients.
-
Post-Surgical Therapy – Reduces the risk of cancer recurrence after surgery.
-
Symptom Management in Prostate Cancer – Relieves pain, urinary difficulties, and other cancer-related symptoms.
How Prostiga 250 mg Works (Mechanism of Action):
Prostiga (Abiraterone Acetate) is a CYP17 enzyme inhibitor that blocks testosterone production, which fuels prostate cancer growth.
-
Inhibits the CYP17 enzyme, a key enzyme involved in testosterone synthesis.
-
Reduces androgen production in the testes, adrenal glands, and prostate tumor cells.
-
Slows down tumor growth by depriving cancer cells of testosterone.
-
Used with prednisone to counteract side effects such as high blood pressure and fluid retention.
Dosage of Prostiga 250 mg
Recommended Dosage:
-
Standard Dose: 1000 mg per day (Four 250 mg tablets taken once daily)
-
Prednisone Required: 5 mg twice daily
-
Dose Adjustments: May be needed for patients with liver problems or severe side effects.
Dosage Adjustments for Liver Issues:
-
Patients with moderate liver impairment may require a lower dose.
-
Frequent liver function tests are necessary to prevent toxicity.
Method of Administration (How to Take It)
-
Take Prostiga on an empty stomach – at least 1 hour before or 2 hours after a meal.
-
Swallow the tablets whole with a full glass of water.
-
Do not chew, crush, or break the tablets before swallowing.
-
Take the medication at the same time every day for consistent drug levels.
-
Prednisone must be taken alongside Prostiga to reduce side effects.
Side Effects of Prostiga 250 mg
Common Side Effects:
-
Fatigue & Weakness
-
High blood pressure (Hypertension)
-
Swelling in legs or feet (Fluid retention/Edema)
-
Low potassium levels (Hypokalemia)
-
Hot flashes & excessive sweating
-
Increased liver enzyme levels
-
Joint pain (Arthralgia)
Severe Side Effects:
-
Heart problems (Irregular heartbeat, Chest pain, Heart failure)
-
Severe liver damage (Jaundice, Hepatitis, Elevated liver enzymes)
-
Adrenal insufficiency (Dizziness, Weakness, Low blood pressure, Salt imbalance)
-
Severe allergic reactions (Rash, Itching, Swelling, Difficulty breathing)
⚠️ Seek immediate medical attention if you experience chest pain, severe dizziness, or yellowing of the skin (jaundice).
Precautions Before Taking Prostiga 250 mg
-
Not for use in women or children – May cause serious harm if taken by pregnant women.
-
Regular blood tests required – Liver function, blood pressure, and potassium levels must be monitored.
-
Patients with heart disease should use caution – Increased risk of heart complications.
-
Avoid grapefruit and grapefruit juice – It can increase the risk of side effects.
-
Use effective contraception – Male patients should take precautions to prevent pregnancy in their partners.
Drug Interactions (Medications That May Interact)
Prostiga 250 mg can interact with several medications, including:
Avoid using with:
-
Strong CYP3A4 inducers (e.g., Rifampin, Carbamazepine) – May reduce effectiveness.
-
CYP2D6 substrates (e.g., Metoprolol, Codeine) – Can alter drug levels.
-
Blood thinners (Warfarin, Heparin) – May increase the risk of bleeding.
-
Corticosteroids (other than prednisone) – Can interfere with hormone balance.
-
Heart medications (Digoxin, Amiodarone) – Can cause heart complications.
Allergy Warnings
-
Do not use if allergic to Abiraterone Acetate or any ingredients in Prostiga.
-
Signs of allergy: Rash, swelling, itching, difficulty breathing.
-
Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
-
Store at room temperature (15-30°C or 59-86°F).
-
Keep in a dry place, away from moisture and direct sunlight.
-
Keep out of reach of children.
-
Do not use expired medication.
Overdose Information
Symptoms of overdose:
-
Severe dizziness or fainting
-
Irregular heartbeat
-
Confusion or difficulty breathing
What to do in case of overdose?
-
Seek emergency medical help immediately.
-
Visit the nearest hospital or call a poison control center.
Missed Dose Instructions
-
If you miss a dose, take it as soon as you remember.
-
If it is almost time for the next dose, skip the missed dose—do not take a double dose.
-
Never take extra tablets to make up for a missed dose.
Additional Notes:
-
Regular medical check-ups are necessary to monitor liver function, potassium levels, and blood pressure.
-
Do not stop taking Prostiga suddenly without consulting your doctor.
-
A balanced diet, exercise, and a healthy lifestyle may improve treatment outcomes.
Product Introduction:
Prostiga 250 mg is a hormonal therapy drug used in metastatic prostate cancer. Prostate cancer cells depend on testosterone to grow and spread, and this medication helps reduce testosterone production, slowing the progression of the disease.
Prednisone is prescribed alongside Prostiga to prevent side effects such as high blood pressure and fluid retention.
Uses of Prostiga 250 mg
Prostiga is primarily used for treating advanced-stage prostate cancer, including:
-
Metastatic Castration-Resistant Prostate Cancer (mCRPC) – For patients whose cancer continues to grow despite previous hormonal therapy or surgical castration.
-
Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) – For newly diagnosed advanced prostate cancer to slow progression.
-
Delaying Chemotherapy – Helps in postponing chemotherapy in advanced prostate cancer patients.
-
Post-Surgical Therapy – Reduces the risk of cancer recurrence after surgery.
-
Symptom Management in Prostate Cancer – Relieves pain, urinary difficulties, and other cancer-related symptoms.
How Prostiga 250 mg Works (Mechanism of Action):
Prostiga (Abiraterone Acetate) is a CYP17 enzyme inhibitor that blocks testosterone production, which fuels prostate cancer growth.
-
Inhibits the CYP17 enzyme, a key enzyme involved in testosterone synthesis.
-
Reduces androgen production in the testes, adrenal glands, and prostate tumor cells.
-
Slows down tumor growth by depriving cancer cells of testosterone.
-
Used with prednisone to counteract side effects such as high blood pressure and fluid retention.
Dosage of Prostiga 250 mg
Recommended Dosage:
-
Standard Dose: 1000 mg per day (Four 250 mg tablets taken once daily)
-
Prednisone Required: 5 mg twice daily
-
Dose Adjustments: May be needed for patients with liver problems or severe side effects.
Dosage Adjustments for Liver Issues:
-
Patients with moderate liver impairment may require a lower dose.
-
Frequent liver function tests are necessary to prevent toxicity.
Method of Administration (How to Take It)
-
Take Prostiga on an empty stomach – at least 1 hour before or 2 hours after a meal.
-
Swallow the tablets whole with a full glass of water.
-
Do not chew, crush, or break the tablets before swallowing.
-
Take the medication at the same time every day for consistent drug levels.
-
Prednisone must be taken alongside Prostiga to reduce side effects.
Side Effects of Prostiga 250 mg
Common Side Effects:
-
Fatigue & Weakness
-
High blood pressure (Hypertension)
-
Swelling in legs or feet (Fluid retention/Edema)
-
Low potassium levels (Hypokalemia)
-
Hot flashes & excessive sweating
-
Increased liver enzyme levels
-
Joint pain (Arthralgia)
Severe Side Effects:
-
Heart problems (Irregular heartbeat, Chest pain, Heart failure)
-
Severe liver damage (Jaundice, Hepatitis, Elevated liver enzymes)
-
Adrenal insufficiency (Dizziness, Weakness, Low blood pressure, Salt imbalance)
-
Severe allergic reactions (Rash, Itching, Swelling, Difficulty breathing)
⚠️ Seek immediate medical attention if you experience chest pain, severe dizziness, or yellowing of the skin (jaundice).
Precautions Before Taking Prostiga 250 mg
-
Not for use in women or children – May cause serious harm if taken by pregnant women.
-
Regular blood tests required – Liver function, blood pressure, and potassium levels must be monitored.
-
Patients with heart disease should use caution – Increased risk of heart complications.
-
Avoid grapefruit and grapefruit juice – It can increase the risk of side effects.
-
Use effective contraception – Male patients should take precautions to prevent pregnancy in their partners.
Drug Interactions (Medications That May Interact)
Prostiga 250 mg can interact with several medications, including:
Avoid using with:
-
Strong CYP3A4 inducers (e.g., Rifampin, Carbamazepine) – May reduce effectiveness.
-
CYP2D6 substrates (e.g., Metoprolol, Codeine) – Can alter drug levels.
-
Blood thinners (Warfarin, Heparin) – May increase the risk of bleeding.
-
Corticosteroids (other than prednisone) – Can interfere with hormone balance.
-
Heart medications (Digoxin, Amiodarone) – Can cause heart complications.
Allergy Warnings
-
Do not use if allergic to Abiraterone Acetate or any ingredients in Prostiga.
-
Signs of allergy: Rash, swelling, itching, difficulty breathing.
-
Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
-
Store at room temperature (15-30°C or 59-86°F).
-
Keep in a dry place, away from moisture and direct sunlight.
-
Keep out of reach of children.
-
Do not use expired medication.
Overdose Information
Symptoms of overdose:
-
Severe dizziness or fainting
-
Irregular heartbeat
-
Confusion or difficulty breathing
What to do in case of overdose?
-
Seek emergency medical help immediately.
-
Visit the nearest hospital or call a poison control center.
Missed Dose Instructions
-
If you miss a dose, take it as soon as you remember.
-
If it is almost time for the next dose, skip the missed dose—do not take a double dose.
-
Never take extra tablets to make up for a missed dose.
Additional Notes:
-
Regular medical check-ups are necessary to monitor liver function, potassium levels, and blood pressure.
-
Do not stop taking Prostiga suddenly without consulting your doctor.
-
A balanced diet, exercise, and a healthy lifestyle may improve treatment outcomes.
