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Pryor 60mg - Apalutamide Tablets

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Pryor 60mg - Apalutamide Tablets

Pryor 60 mg contains Apalutamide, an androgen receptor inhibitor used to treat non-metastatic and metastatic castration-resistant prostate cancer (CRPC) and metastatic castration-sensitive prostate cancer (mCSPC). It works by blocking the effects of androgens (male hormones) like testosterone, thereby slowing the growth of prostate cancer cells.

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Description Product Details
General Information:
Generic Name: Apalutamide
Brand Name: Pryor
Packing: 60 Tablets
Strength: 60 mg
Manufacturer: BDR Pharmaceuticals Int'I Pvt. Ltd.
Form: Oral tablet
Category: Anti-androgen, Anti-Cancer Drug
Product Introduction:
Pryor 60 mg is a next-generation androgen receptor inhibitor designed to treat advanced prostate cancer. It effectively blocks testosterone-driven cancer cell growth, helping to slow disease progression and improve survival rates. It is commonly used in combination with androgen deprivation therapy (ADT).
Uses of Pryor 60 mg
Pryor 60 mg is commonly prescribed for:
  1. Non-Metastatic Castration-Resistant Prostate Cancer (nmCRPC) – Helps delay cancer spread in patients with high PSA levels.
  2. Metastatic Castration-Resistant Prostate Cancer (mCRPC) – Treats advanced prostate cancer that no longer responds to ADT.
  3. Metastatic Castration-Sensitive Prostate Cancer (mCSPC) – Used alongside ADT to control early metastatic prostate cancer.
  4. PSA Progression Control – Helps slow PSA doubling time, reducing the risk of metastasis.
  5. Delaying Chemotherapy – Used to delay the need for chemotherapy in prostate cancer patients.
How Pryor 60 mg Works (Mechanism of Action):
  1. Apalutamide blocks androgen receptors, preventing testosterone and dihydrotestosterone (DHT) from binding.
  2. Without testosterone stimulation, prostate cancer cells lose their growth signal and slow down.
  3. Unlike older anti-androgens, Apalutamide also prevents nuclear translocation, making it more effective than earlier treatments.
  4. This leads to slower disease progression, delayed metastasis, and improved survival.
Dosage of Pryor 60 mg
Recommended Dosage:
  1. Standard dose: 240 mg (four 60 mg tablets) once daily.
  2. Treatment duration: Continued until disease progression or unacceptable toxicity.
📌 Dosage may be adjusted based on tolerance and side effects. Always follow your doctor's prescription.
Method of Administration (How to Take It)
  1. Take four 60 mg tablets (total 240 mg) once daily.
  2. Can be taken with or without food.
  3. Swallow tablets whole with water—do not crush, chew, or break them.
  4. Take at the same time every day to maintain stable drug levels.
  5. If vomiting occurs after taking the dose, do not retake it—wait for the next scheduled dose.
Side Effects of Pryor 60 mg
Common Side Effects:
  1. Fatigue and weakness
  2. High blood pressure (hypertension)
  3. Rash and skin irritation
  4. Joint pain and muscle weakness
  5. Hot flashes
  6. Decreased appetite and weight loss
Severe Side Effects (Seek Medical Help Immediately):
  1. Seizures – Risk of convulsions due to nervous system effects.
  2. Heart problems – Shortness of breath, chest pain, irregular heartbeat.
  3. Fractures and falls – Increased risk of osteoporosis and bone fractures.
  4. Liver damage – Symptoms include yellow skin, dark urine, and severe abdominal pain.
  5. Severe allergic reactions – Swelling of face, throat, difficulty breathing, rash.
⚠️ Regular monitoring of heart function, bone health, and liver enzymes is recommended.
Precautions Before Taking Pryor 60 mg
  1. Seizure Risk: Patients with a history of epilepsy or brain injury should use this medication with caution.
  2. Bone Health: Increases risk of osteoporosis and fractures—calcium and vitamin D supplements may be needed.
  3. Heart Conditions: May cause high blood pressure or heart disease—regular monitoring required.
  4. Liver or Kidney Disease: Requires dose adjustment or close monitoring.
  5. Pregnancy & Breastfeeding: Not for use in women—can cause severe harm to an unborn baby.
Drug Interactions (Medications That May Interact)
Pryor 60 mg can interact with:
  1. Warfarin & Blood Thinners – Increases bleeding risk.
  2. Anti-Seizure Medications (Phenytoin, Carbamazepine) – May reduce Apalutamide effectiveness.
  3. CYP3A4 Inhibitors (Rifampin, Ketoconazole, Clarithromycin) – Can alter Apalutamide metabolism.
  4. Diabetes Medications (Metformin, Insulin) – May affect blood sugar levels.
  5. Hormonal Therapies (Testosterone Replacement Therapy, Estrogen Drugs) – Counteracts the drug’s effects.
⚠️ Inform your doctor about all medications and supplements before starting Pryor 60 mg.
Allergy Warnings
  1. Do not take Pryor 60 mg if allergic to Apalutamide or its ingredients.
  2. Signs of an allergic reaction:
    1. Swelling of face, lips, or throat
    2. Difficulty breathing
    3. Severe rash or itching
    4. Dizziness or fainting
🚨 Seek emergency medical help if an allergic reaction occurs.
Storage Instructions
  1. Store at room temperature (15°C - 30°C / 59°F - 86°F).
  2. Keep in original packaging to protect from moisture and light.
  3. Keep away from children and pets.
Overdose Information
Symptoms of overdose:
  1. Severe weakness or drowsiness
  2. Seizures
  3. Irregular heartbeat or fainting
  4. High blood pressure crisis
What to do in case of overdose?
  1. Seek immediate medical attention.
  2. Hospitalization may be required for supportive care.
Missed Dose Instructions
  1. If missed by less than 12 hours: Take the dose as soon as possible.
  2. If missed by more than 12 hours: Skip the missed dose and take the next scheduled dose.
  3. Do not take a double dose to make up for a missed one.
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