Nextgen Biotech

Call us:

Sazobact 3mg - Cefoperazone & Sulbactam For Injection

Sazobact 3g is a combination antibiotic injection containing Cefoperazone (a cephalosporin antibiotic) and Sulbactam (a beta-lactamase inhibitor). It is used to treat severe bacterial infections such as respiratory tract infections, urinary tract infections, intra-abdominal infections, and sepsis.

Choose Quantity:

-
+
Share
General Information:
Generic Name: Cefoperazone & Sulbactam
Brand Name: Sazobact
Packing: Vial
Strength: 3g (Cefoperazone 2g + Sulbactam 1g)
Manufacturer: Smithways Health Care Pvt.Ltd.
Form: Injection (Intravenous/Intramuscular Use)
Category: Antibiotic (Cephalosporin + Beta-lactamase Inhibitor)
Product Introduction:
Sazobact 3g is a broad-spectrum antibiotic used for treating moderate to severe bacterial infections. The combination of Cefoperazone and Sulbactam enhances its effectiveness against resistant bacteria.

Uses of Sazobact 3g
Sazobact 3g is used to treat:
  1. Respiratory Tract Infections – Pneumonia, bronchitis, and lung infections.
  2. Urinary Tract Infections (UTIs) – Including complicated UTIs caused by resistant bacteria.
  3. Intra-Abdominal Infections – Peritonitis, appendicitis, and abdominal abscesses.
  4. Skin & Soft Tissue Infections – Cellulitis, wound infections, and diabetic foot infections.
  5. Sepsis (Bloodstream Infections) – Effective against hospital-acquired infections.
  6. Gynecological Infections – Pelvic inflammatory disease (PID) and post-surgical infections.

How Sazobact 3g Works (Mechanism of Action):
  1. Cefoperazone: A third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial death.
  2. Sulbactam: A beta-lactamase inhibitor that prevents bacteria from breaking down Cefoperazone, making the antibiotic more effective against resistant bacteria.
This combination provides a stronger and broader antibacterial effect.

Dosage of Sazobact 3g
Typical Recommended Dose:
  1. Adults: 1.5g – 3g every 12 hours (IV or IM).
  2. Severe Infections: Dose may be increased up to 6g per day in divided doses.
  3. Children: 50–100 mg/kg/day in divided doses (Consult doctor for pediatric dosing).
⚠️ Dosage may vary based on infection type, severity, and kidney function.

Method of Administration (How to Take It)
  1. Intravenous (IV) Infusion: Dilute with saline or dextrose and infuse over 15–30 minutes.
  2. Intramuscular (IM) Injection: Can be given deep into a muscle after dilution.
💡 IV administration is preferred for severe infections.

Side Effects of Sazobact 3g
Common Side Effects:
  1. Nausea & Vomiting
  2. Diarrhea
  3. Pain at the injection site
  4. Mild skin rash or itching
Severe Side Effects (Seek Immediate Medical Help):
  1. Severe allergic reactions (swelling, difficulty breathing, hives)
  2. Severe diarrhea (indicating Clostridium difficile infection)
  3. Liver dysfunction (yellowing of skin, dark urine, abdominal pain)
  4. Severe skin reactions (Stevens-Johnson syndrome)
🚨 Contact a doctor if severe symptoms occur.

Precautions Before Taking Sazobact 3g
  1. Kidney or Liver Disease: Requires dose adjustment.
  2. Bleeding Disorders: Cefoperazone can affect blood clotting.
  3. Pregnancy & Breastfeeding: Safe if prescribed but should be used with caution.
  4. Previous Allergy to Cephalosporins/Penicillins: May cause severe reactions.
  5. Alcohol Use: Avoid alcohol during treatment as it may cause a disulfiram-like reaction (nausea, vomiting, flushing).

Drug Interactions (Medications That May Interact)
Sazobact 3g may interact with:
  1. Blood Thinners (Warfarin, Heparin): Increases bleeding risk.
  2. Aminoglycoside Antibiotics (Gentamicin, Amikacin): May increase kidney toxicity.
  3. Diuretics (Furosemide, Hydrochlorothiazide): May worsen kidney function.
  4. NSAIDs (Ibuprofen, Aspirin): May increase bleeding risk.
  5. Alcohol: Can cause severe nausea, vomiting, and dizziness.
⚠️ Inform your doctor about all medications you are taking.

Allergy Warnings
  1. Do not take if allergic to Cefoperazone, Sulbactam, or other cephalosporin antibiotics.
  2. Symptoms of an allergic reaction:
    1. Rash, Itching
    2. Swelling of face or throat
    3. Difficulty breathing
    4. Severe dizziness
🚨 Seek emergency medical help if allergic symptoms occur.

Storage Instructions
  1. Store below 25°C in a dry place.
  2. Keep in the original packaging, protected from light.
  3. Reconstituted solution should be used immediately or stored as per manufacturer’s instructions.
  4. Keep out of reach of children.

Overdose Information
Symptoms of Overdose:
  1. Severe diarrhea
  2. Seizures (in rare cases)
  3. Severe allergic reaction
What to Do in Case of Overdose?
  1. Seek emergency medical help immediately.
  2. Hospitalization may be required for supportive treatment.

Missed Dose Instructions
  1. If a dose is missed, take it as soon as possible.
  2. If it’s almost time for the next dose, skip the missed dose.
  3. Do not double the dose.

In The Same Category

Cart