Product Intro:
Zoladex 3.6mg is a subcutaneous implant injection containing Goserelin Acetate, a gonadotropin-releasing hormone (GnRH) agonist. It is used to reduce hormone levels in patients with hormone-dependent cancers or gynecological issues such as endometriosis.
Uses:
Zoladex 3.6mg is used in the treatment of:
-
Prostate cancer
-
Breast cancer (hormone-sensitive)
-
Endometriosis
-
Uterine fibroids (as part of pre-surgical treatment)
-
Fertility treatments (as part of controlled ovarian hyperstimulation)
-
Menorrhagia (heavy menstrual bleeding)
Storage Instructions:
How it Works (Mechanism of Action):
Goserelin is a GnRH agonist. Initially, it stimulates the pituitary gland to increase LH and FSH, causing a temporary rise in estrogen/testosterone levels. Continued use leads to downregulation of receptors, significantly reducing sex hormone levels, mimicking a chemical menopause or castration.
Side Effects:
Common Side Effects:
Severe Side Effects:
Dosage (Typical Recommended Dose):
-
3.6mg subcutaneously every 28 days
-
Administered under the skin in the abdominal wall
-
Dosage and duration depend on the condition being treated
Method of Administration:
-
Administered via subcutaneous injection using a prefilled syringe
-
Must be given by a healthcare professional
-
Rotating injection sites is not required for this formulation
Precautions:
-
Not recommended during pregnancy or breastfeeding
-
Monitor bone mineral density in long-term use
-
Caution in patients with depression, diabetes, or cardiovascular conditions
-
Tumor flare prevention in prostate cancer patients may require anti-androgens during initiation
-
Regular hormone level monitoring may be necessary
Drug Interactions:
-
No significant interactions with most drugs
-
May interact with hormone therapies or fertility medications
-
Always inform your doctor of all current medications and supplements
Allergies:
-
Do not use if allergic to Goserelin or other GnRH analogs
-
Symptoms of allergic reaction include rash, itching, swelling, dizziness, and difficulty breathing
Overdose Information:
-
Overdose is unlikely due to controlled release formulation
-
Symptoms could include prolonged hormone suppression and associated side effects
-
Seek immediate medical attention if overdose is suspected
Missed Dose Instructions:
-
Contact your healthcare provider if a scheduled dose is missed
-
Do not attempt self-injection or delay medical consultation
-
Timely administration is crucial for continuous hormone suppression
Additional Notes:
-
Bone health supplements (calcium, vitamin D) may be recommended
-
Patients should be aware of signs of depression or bone pain
-
Can temporarily worsen symptoms before improvement begins ("tumor flare")
Product Intro:
Zoladex 3.6mg is a subcutaneous implant injection containing Goserelin Acetate, a gonadotropin-releasing hormone (GnRH) agonist. It is used to reduce hormone levels in patients with hormone-dependent cancers or gynecological issues such as endometriosis.
Uses:
Zoladex 3.6mg is used in the treatment of:
-
Prostate cancer
-
Breast cancer (hormone-sensitive)
-
Endometriosis
-
Uterine fibroids (as part of pre-surgical treatment)
-
Fertility treatments (as part of controlled ovarian hyperstimulation)
-
Menorrhagia (heavy menstrual bleeding)
Storage Instructions:
How it Works (Mechanism of Action):
Goserelin is a GnRH agonist. Initially, it stimulates the pituitary gland to increase LH and FSH, causing a temporary rise in estrogen/testosterone levels. Continued use leads to downregulation of receptors, significantly reducing sex hormone levels, mimicking a chemical menopause or castration.
Side Effects:
Common Side Effects:
Severe Side Effects:
Dosage (Typical Recommended Dose):
-
3.6mg subcutaneously every 28 days
-
Administered under the skin in the abdominal wall
-
Dosage and duration depend on the condition being treated
Method of Administration:
-
Administered via subcutaneous injection using a prefilled syringe
-
Must be given by a healthcare professional
-
Rotating injection sites is not required for this formulation
Precautions:
-
Not recommended during pregnancy or breastfeeding
-
Monitor bone mineral density in long-term use
-
Caution in patients with depression, diabetes, or cardiovascular conditions
-
Tumor flare prevention in prostate cancer patients may require anti-androgens during initiation
-
Regular hormone level monitoring may be necessary
Drug Interactions:
-
No significant interactions with most drugs
-
May interact with hormone therapies or fertility medications
-
Always inform your doctor of all current medications and supplements
Allergies:
-
Do not use if allergic to Goserelin or other GnRH analogs
-
Symptoms of allergic reaction include rash, itching, swelling, dizziness, and difficulty breathing
Overdose Information:
-
Overdose is unlikely due to controlled release formulation
-
Symptoms could include prolonged hormone suppression and associated side effects
-
Seek immediate medical attention if overdose is suspected
Missed Dose Instructions:
-
Contact your healthcare provider if a scheduled dose is missed
-
Do not attempt self-injection or delay medical consultation
-
Timely administration is crucial for continuous hormone suppression
Additional Notes:
-
Bone health supplements (calcium, vitamin D) may be recommended
-
Patients should be aware of signs of depression or bone pain
-
Can temporarily worsen symptoms before improvement begins ("tumor flare")
