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Gempower 1gm - Gemcitabine for Injection

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Gempower 1gm - Gemcitabine for Injection

Gempower 1gm is a potent chemotherapy injection used in the treatment of various cancers including pancreatic, lung, breast, and ovarian cancer. It works by slowing or stopping the growth of cancer cells in the body.

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Description Product Details
General Information:
Generic Name: Gemcitabine Hydrochloride
Brand Name: Gempower
Packing: Single-use vial
Strength: 1 gram (1000mg)
Manufacturer: Khandelwal Laboratories Pvt.Ltd
Form: Lyophilized Powder for Injection
Category: Chemotherapy / Antineoplastic / Antimetabolite
Product Intro:
Gempower 1gm is an anti-cancer injectable medication containing the active ingredient Gemcitabine. It is used in multiple cancer therapies and must be administered under the guidance of a healthcare professional in a hospital or clinical setting.
Uses:
Gempower 1gm is indicated for the treatment of:
  1. Non-Small Cell Lung Cancer (NSCLC)
  2. Pancreatic Cancer
  3. Breast Cancer
  4. Ovarian Cancer
  5. Bladder Cancer
  6. Cholangiocarcinoma (bile duct cancer)
Storage Instructions:
  1. Store below 25°C
  2. Keep the vial in the original packaging, protected from light
  3. Reconstituted solution should be used promptly or stored refrigerated (2°C–8°C) for up to 24 hours
  4. Do not freeze
How it Works (Mechanism of Action):
Gemcitabine is a pyrimidine nucleoside analog. It is incorporated into DNA during the S-phase of cell division, halting DNA synthesis. It also inhibits ribonucleotide reductase, which is necessary for DNA replication, thereby inducing cancer cell death.
Side Effects:
Common Side Effects:
  1. Nausea and vomiting
  2. Anemia (low red blood cells)
  3. Neutropenia (low white blood cells)
  4. Fatigue
  5. Mild rash
  6. Fever
Severe Side Effects:
  1. Pulmonary toxicity
  2. Liver dysfunction
  3. Renal impairment
  4. Severe bone marrow suppression
  5. Hemolytic uremic syndrome (rare but serious)
Dosage (Typical Recommended Dose): 
  1. Usual dose: 1000 mg/m² intravenously on days 1, 8, and 15 of a 28-day cycle
  2. Dosage may vary based on type of cancer, patient’s body surface area, and blood count
  3. Dose adjustments may be required based on response and side effects
Method of Administration:
  1. Administered via intravenous (IV) infusion
  2. Infusion usually lasts 30 minutes
  3. Should only be given under the supervision of trained oncology professionals
  4. Reconstituted with sterile saline or dextrose for injection
Precautions:
  1. Not to be used in pregnancy or breastfeeding
  2. Use contraception during and after treatment
  3. Regular monitoring of blood cell counts, renal, and liver functions is necessary
  4. Avoid contact with individuals who have infections
  5. Inform doctor if you experience persistent cough, bleeding, or unusual bruising
Drug Interactions:
  1. Increased risk of toxicity with cisplatin
  2. Avoid live vaccines during treatment
  3. May interact with warfarin (monitor INR levels)
  4. Inform healthcare provider of all ongoing medications
Allergies:
  1. Contraindicated in patients with known allergy to Gemcitabine
  2. Watch for signs like rash, swelling, or breathing difficulty
  3. Discontinue immediately if hypersensitivity occurs
Overdose Information:
  1. Symptoms may include severe drop in blood counts, liver/kidney damage, or serious infections
  2. No specific antidote; requires hospitalization and supportive treatment
  3. Close monitoring is essential
Missed Dose Instructions:
  1. If a dose is missed, consult your oncologist immediately
  2. Do not attempt to self-medicate or adjust the schedule
  3. Your doctor will advise on how to proceed safely
Additional Notes:
  1. Ensure proper hydration before and after infusion
  2. Follow a balanced diet to support recovery
  3. Regular lab tests are crucial to monitor drug impact
  4. Only trained medical professionals should handle and dispose of the drug and related materials
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