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Pomide 4mg - Pomalidomide Capsules

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Pomide 4mg - Pomalidomide Capsules

Pomide 4mg contains Pomalidomide, an immunomodulatory agent used to treat multiple myeloma, especially in patients who have already undergone other treatments. It works by enhancing the immune system and inhibiting the growth of cancer cells.

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Description Product Details
General Information:
Generic Name: Pomalidomide
Brand Name: Pomide
Packing: Bottle of 21 capsules
Strength: 4 mg
Manufacturer: Natco Pharma Ltd
Form: Capsule
Category: Anti-cancer, Immunomodulatory Agent, Chemotherapy Adjuvant
Product Intro:
Pomide 4mg is a prescription medication used in combination with other drugs for the treatment of relapsed or refractory multiple myeloma in adult patients. It belongs to a class of medications called immunomodulatory drugs (IMiDs) and is known for its dual action: stimulating the immune system and directly affecting the growth of myeloma cells.
Uses:
  1. Treatment of multiple myeloma in patients who have received at least two prior therapies
  2. Used in combination with dexamethasone
  3. Helps reduce the growth and survival of myeloma cells
  4. Stimulates T-cell and natural killer (NK) cell activity
  5. Modulates the immune response to target cancer cells
  6. May reduce inflammation and angiogenesis in tumor tissues
Storage Instructions:
  1. Store at room temperature, between 15°C to 30°C (59°F to 86°F)
  2. Protect from moisture and light
  3. Keep out of reach of children and pets
  4. Handle with care — do not open capsules
How it Works (Mechanism of Action):
Pomalidomide works through multiple mechanisms:
  1. Enhances T-cell and NK-cell mediated immunity, promoting the destruction of cancer cells
  2. Inhibits angiogenesis, thus starving the tumor of blood supply
  3. Directly affects myeloma cell growth and induces apoptosis (programmed cell death)
  4. Suppresses pro-inflammatory cytokines in the bone marrow microenvironment
Side Effects:
Common Side Effects:
  1. Fatigue
  2. Nausea
  3. Constipation or diarrhea
  4. Dizziness
  5. Loss of appetite
  6. Back pain
  7. Swelling of hands or feet
Severe Side Effects:
  1. Neutropenia (low white blood cells)
  2. Anemia or thrombocytopenia
  3. Blood clots (deep vein thrombosis, pulmonary embolism)
  4. Liver enzyme elevations
  5. Secondary malignancies (rare)
  6. Infections due to immunosuppression
Dosage (Typical Recommended Dose):
  1. 4 mg once daily on days 1 to 21 of each 28-day cycle
  2. Always taken in combination with dexamethasone
  3. Dose adjustments may be required based on tolerance and lab results
Method of Administration:
  1. Take orally with or without food
  2. Swallow the capsule whole with water — do not open, chew, or crush
  3. Take at the same time each day for consistency
  4. Always follow the exact dosage schedule prescribed by your doctor
Precautions:
  1. Pregnancy Warning: Pomalidomide is highly teratogenic – must not be taken during pregnancy
  2. Use two forms of contraception if of childbearing potential
  3. Regular blood tests required to monitor blood counts and liver function
  4. Caution in patients with kidney or liver impairment
  5. Avoid driving or operating machinery if feeling dizzy or tired
Drug Interactions:
  1. Increased risk of side effects with strong CYP1A2 and CYP3A4 inhibitors
  2. Can interact with blood thinners and chemotherapy agents
  3. May alter effects of drugs like dexamethasone, warfarin, and erythropoietin
  4. Avoid using with St. John’s Wort or other herbal supplements
Allergies:
  1. Do not use if allergic to Pomalidomide or similar drugs like Thalidomide or Lenalidomide
  2. Allergic reactions may include rash, itching, swelling, severe dizziness, or difficulty breathing
Overdose Information:
  1. Symptoms may include severe fatigue, infections, unusual bleeding
  2. Seek emergency medical attention immediately
  3. No specific antidote — supportive treatment required
Missed Dose Instructions:
  1. If missed and less than 12 hours late, take it immediately
  2. If more than 12 hours have passed, skip the missed dose
  3. Do not double dose to make up for a missed one
Additional Notes:
  1. Pomalidomide is only available under strict distribution programs due to its risk of birth defects (REMS program in some countries)
  2. Male patients must also use effective contraception if partner is of childbearing age
  3. Periodic lab tests and physical exams are essential during treatment
  4. Wash hands after handling capsules and avoid contact with broken capsules
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